山莨菪碱对烫伤小鼠创面的治疗作用及机制  

Primary study of therapeutical effect and mechanism of anisodamine on scalding injury

作　　者：赵小歌[1] 罗琳[1] 徐济良[1] 王洋[1] 

机构地区：[1]南通大学药理学教研室,南通226001

出　　处：《南通大学学报（医学版）》2005年第3期185-186,共2页Journal of Nantong University(Medical sciences)

摘　　要：目的:观察山莨菪碱对烫伤小鼠创面的治疗作用并初步探讨其机制。方法:建立小鼠烫伤模型,观察各实验组动物经不同处理后烫伤创面恢复情况,并检测血清MDA的含量。结果:山莨菪碱能加速烫伤创面愈合,降低烫伤小鼠血清MDA含量。结论:山莨菪碱通过抑制脂质过氧化反应减轻烫伤创面损伤。Objective:To observe therapeutical effect of anisodamine on scalding injury and study its mechanism.Methods:To establish the scalded model of mice,study the scalded wound surface of each group of mice by different treatments,and detect the blood serum content of MDA.Results:Anisodamine could cure the scalded wound surface and reduce the blood serum content of MDA.Conclusion:Anisodamine can relieve the scalding injury by inhibiting lipid peroxidation reaction.

关 键 词：治疗作用 小鼠 山茛菪碱 血清MDA含量 脂质过氧化反应 山莨菪碱 烫伤创面愈合 初步探讨 烫伤模型 恢复情况 不同处 实验组 

分 类 号：R285.5[医药卫生—中药学] R971.92[医药卫生—中医学]