薄层扫描法测定汝安膜中盐酸小檗碱的含量  

Determination of berberine hydrochloride contents of RU AN membrane with thin layer scanning

作　　者：郭新社[1] 李武营[2] 

机构地区：[1]河南大学药学院药物分析教研室,河南开封475001 [2]河南大学学报编辑部,河南开封475001

出　　处：《河南大学学报（医学版）》2005年第2期8-9,共2页Journal of Henan University:Medical Science

基　　金：河南省科技攻关项目;开封市科技攻关项目(030003)。

摘　　要：目的建立汝安膜中盐酸小檗碱的含量测定方法。方法采用薄层扫描法对汝安膜中的盐酸小檗碱进行定量。结果盐酸小檗碱点样量在0.05～0.5μg呈良好的线性关系,平均回收率为99.22%,RSD=1.2%(n=6)。结论该方法准确、可靠、重现性好,可作为该膜剂的质量控制方法。Objective: To establish the method of detecting berberine hydrochloride contents of RU AN membrane.Methods: Berberine hydrochloride contents of RU AN membrane was quantitatively determined with thin layer scanning. Results: The dot sample of berberine hydrochloride contents of RU AN membrane appeared better linear relation on 0.05 ~ 0.5μg,the recovery rate was 99.22% on average,RSD =1.2 %(n = 6).Conclusion: It is accurate, safe, good in the reappearing rate, and can be used as the quality control method for the membrane medication.

关 键 词：汝安膜 盐酸小檗碱 薄层扫描法 

分 类 号：R917.2[医药卫生—药物分析学]