丹栀逍遥丸质量标准的研究  

Studies on Quality Standard of Danzhi Xiaoyo Pills

作　　者：南淑华 

机构地区：[1]厦门中药厂有限公司,厦门361009

出　　处：《海峡药学》2005年第3期88-91,共4页Strait Pharmaceutical Journal

摘　　要：目的建立丹栀逍遥丸的质量控制标准。方法采用显微鉴别法对制剂中的茯苓、柴胡、牡丹皮、白术进行定性鉴别,用薄层色谱法对制剂中的当归、甘草进行定性鉴别,并采用高效液相色谱法对制剂中的栀子苷进行含量测定。结果显微检出茯苓、柴胡、牡丹皮、白术,TLC法检出当归、甘草,栀子苷含量测定的平均回收率为99.5%,RSD为1.57%(n=9)。结论该方法专属性强、简便快速,重现性好,可作为该制剂的质量控制标准。OBJECTIVE To set the quality standard of Danzhi xiaoyao Pills.METHODS Microscopy was used for the identification of Rhizoma Atractylodis Macroce,Poria,Radix Bupleuri and Cortex Moutan.TLC was used for the identification of Radix Angelicae Sinensis and Radix et Rhizoma.Glycyrrhizae HPLC was used for the determination of geniposide in Danzhi Xiaoyo Pills.RESULTS Rhizoma Atractylodis ,Poria,Radix Bupleuri and Cortex Moutan were identified by Microscopy,Radix Angelicae Sinensis and Radix et Rhizoma Glycyrrhizae were identified by TLC,the average recovery was 99.5%,RSD=1.57%(n=9).CONCLUSION The methods in the article was highly specific simple and rapid, excellent precision, which can be used as the idex of quality contrl.

关 键 词：丹栀逍遥丸 显微鉴别法、薄层鉴别法、桅子苷、高效液相色谱法 

分 类 号：R927.11[医药卫生—药学]