盐酸左氧氟沙星与利巴韦林注射液的配伍考察  

The Compatibility of Levofloxacin Combined with Ribavirin Injection

作　　者：陈国庆[1] 王锦芳[2] 陈振富 

机构地区：[1]福建省级机关医院,福州350003 [2]福建省中医药研究院,福州350003 [3]福建省漳平市医院,漳平363000

出　　处：《海峡药学》2005年第3期17-18,共2页Strait Pharmaceutical Journal

摘　　要：目的考察25℃下8h内,盐酸左氧氟沙星注射液与利巴韦林注射液的配伍稳定性.方法采用紫外分光光度法测定配伍后0～8h内盐酸左氧氟沙星和利巴韦林的含量变化,同时观察其紫外吸收光谱、外观、pH等变化.结果 25℃下8h内,盐酸左氧氟沙星注射液与利巴韦林注射液配伍后含量、紫外吸收光谱、外观、pH几乎无变化.结论 8h内盐酸左氧氟沙星与利巴韦林注射液配伍基本稳定.OBJECTIVE To inspect the stability of compatibility of levofloxacin combined with ribavirin injection at 25℃ for 8 hours.METHODS The content change of levofloxacin and ribavin within 0-8 hours after combination of both drugs by UV spectrophotometry,and the pH was determined by a pH meter.RESULTS A significant change of appearance and pH and content had not been observed.CONCLUSION It is stable within 8 hours at 25℃ after the both drugs combined.

关 键 词：左氧氟沙星 利巴韦林 配伍稳定性 

分 类 号：TQ460.4[化学工程—制药化工]