克痔栓的质量控制  

Quality control of Kezhi suppository

作　　者：杨远荣[1] 祝红达[1] 高逢喜[1] 

机构地区：[1]华中科技大学同济医学院附属荆州医院,湖北荆州434020

出　　处：《中国医院药学杂志》2005年第6期510-512,共3页Chinese Journal of Hospital Pharmacy

摘　　要：目的:建立克痔栓的质量控制标准。方法:采用高效液相色谱法(HPLC)测定主药血竭中血竭素的含量,同时用薄层色谱法(TLC)对制剂中的血竭、黄柏进行鉴别。结果:HPLC线性关系良好,平均回收率为100.7%,RSD为1.32%。薄层图谱斑点清晰,阴性对照无干扰。结论:方法可靠,结果重现性好,可有效地控制该制剂质量。OBJECTIVETo establish a quality control standard for Kezhi suppository.METHODSDracorhodin in Kezhi suppository was determined by HPLC,Sanguis draxonis and Cortex phellodendri were identified by TLC.RESULTSThe average recovery was (100.7%) with RSD of (1.32%).TCL spots were clear.CONCLUSIONThe method is applicable and reliable,which can be used for quality control of the suppository.

关 键 词：克痔栓 血竭素 薄层色谱法 高效液相色谱法 

分 类 号：R927.2[医药卫生—药学]