多电极射频消融治疗原发性肝癌对患者血清IL-8的影响  

The influence of radiofrequency ablation on the level of IL-8 in patients with primary hepatocellular carcinoma

作　　者：华国平[1] 陈萍[2] 徐正府[1] 

机构地区：[1]南通大学附属医院消化内科,南通226001 [2]江苏省南通市第三人民医院肿瘤内科

出　　处：《陕西医学杂志》2005年第7期782-784,共3页Shaanxi Medical Journal

摘　　要：目的:探讨多电极射频消融(RFA)治疗原发性肝癌对患者血清IL-8的影响。方法:采用ELISA法检测20例原发性肝癌患者在RFA治疗前、治疗后10d、30d血清IL-8的水平。结果:B超及CT复查显示:术后10d70%的患者肿瘤体积缩小在20%以上;术后30d,80%的患者肿瘤体积缩小在30%以上;30d血清AFP值下降者占50%。原发性肝癌患者血清IL-8水平明显高于正常对照组,但在治疗前后无明显变化。结论:RFA治疗原发性肝癌对患者血清IL-8的水平无明显影响,肿瘤可能不是导致原发性肝癌患者血清IL-8水平明显升高的主要原因。Objective:To study the influence of radiofrequency ablation(RFA) on the level of IL-8 in patients with primary hepatocellular carcinoma. Methods:Interleukin-8 was measured by ELISA from 20 patients with primary hepatocellular carcinoma before and after RFA 10 days and 30 days RFA. Results:At 10 days, 30 days after the procedure , 20 cases were subjected to color utrasonogrghy and CT scans, respectively. The tumor size decreased by 20% at 10 days in 70% patients, decreased by 30% at 30 days in 80% patients, AFP value decreased in 50% of patients. There was an obvious difference in the serum IL-8 level between normal control and the patients, but no obvious difference among the patients before and after RFA 10 days, 30days. Conclusion:RFA has no influence on the level of IL-8 in patients with primary hepatocellular carcinoma, tumor may be not an important cause of the high level of IL-8 in patients with primary hepatocellular carcinoma.

关 键 词：血清IL-8 多电极射频消融治疗 原发性肝癌患者 射频消融(RFA) ELISA法检测 IL-8水平 体积缩小 正常对照组 CT复查 治疗前后 治疗后 肿瘤 术后 

分 类 号：R692[医药卫生—泌尿科学] R735.7[医药卫生—外科学]