大鼠孤束核内5－羟色胺能轴突终末的突触联系  

SYNAPTIC CONNECTIONS OF THE SEROTONINERGIC AXON TERMINALS IN NUCLEUS TRACTUS SOLITARIUS OF THE RAT

作　　者：陈良为[1] 施际武[1] 饶志仁[1] 

机构地区：[1]第四军医大学解剖学教研室

出　　处：《解剖学报》1994年第3期244-247,T004,共5页Acta Anatomica Sinica

基　　金：国家自然科学基金

摘　　要：用顺行演变与免疫组织化学结合的双标技术，电镜下观察大鼠孤束核内５－羟色胺样免疫反应（５－ＨＴ－ＬＩ）轴突终末的突触联系，特别是与迷走神经初级传入（溃变）终末的关系。发现：１．５－ＨＴ－ＬＩ轴突终末和迷走神经初级传入终末终止于同一个树突形成轴－树突触；２．５－ＨＴ－ＬＩ轴突终末与树突形成轴－树突触；３．５－ＨＴ－ＬＩ轴突终末与迷走神经初级传入终末或非标记的轴突终未形成轴一轴相贴（ａｘｏ－ａｘｏｎｉｃ－ｃｏｎｔａｃｔ）。以上结果提示，孤束核内的５－ＨＴ能神经成分可能通过突触后、突触前机制调控经迷走神经传入的信息。The synaptic connections of the serotonin-like immunoreactive(5-HT-LI)axon terminals,especially their relationship with vagal afferents in the nucleus tractus solitarius(NTS)of the rat were examined under electron microscope by double labelling technique combined with anterograde degeneraton and immunohistochemistry.We found:1.5-HT-LI axon terminals and degenerated axon terminals of the vagal afferents converged on same dendrites;2.5-HT-LI axon terminals formed axo-dendritic synapses with dendrites;3.5-HT-LI axons formed axo-axonic contacts with degenerated vagal afferent axon terminals or with normal axon terminals.These results suggested that in the NTS serotoninerggic neuroelements may modulate the visceral informations via the vagal afferents by postsynaptic mechanism and also possibly by pre-synaptic mechanism.

关 键 词：孤束核 迷走神经 初级传入 血清素 

分 类 号：R322.81[医药卫生—人体解剖和组织胚胎学]