阿司匹林用于冠脉痉挛患者的安全性分析  

The Safety of Aspirin in Coronary Artery Disease Patients with Coronary Spasml

作　　者：刘辉[1] 鲍正宇[1] 陈锐[2] 毛家亮[1] 

机构地区：[1]上海第二医科大学附属仁济医院心内科,上海200127 [2]上海市第八人民医院,上海200233

出　　处：《中国临床医学》2005年第3期540-541,共2页Chinese Journal of Clinical Medicine

摘　　要：目的:探讨阿司匹林在存在冠脉痉挛的冠心患者中应用的安全性。方法:对52例冠心病存在冠脉痉挛的患者,随机分为阿司匹林治疗组和抵克力得治疗组.观察比较2组临床心绞痛发作的情况,经6个月的随访.判断阿司匹林在存在血管痉挛的患者中应用的安全性。结果:经6个月的随访观察,以上2组患者其心绞痛发作的转归无显著差异(P>0.05)。结论:阿司匹林作为一价廉效优的抗血小板药物.不但能应用于劳累型心绞痛的患者,也能安全地应用于存在冠脉血管痉挛的患者。Objective: To evaluate the safety of aspirin in CAD patients with coronary spasm. Methods: 52 CAD patients with coronary spasm were randomly assigned to receive ticlopidine aspirin or Ticlid for 6 months. The anginal changes of two groups were compared and the safety of aspirin in CAD patients with coronary spasm were evaluated. Results: During the 6 months follow-up, the difference of anginal changes between the two groups did not reach statistical significance(PX). 05). Conclusion: As a economical and effective anti-platelet medicine, aspirin can be used not only in patients suffered from angina pectons. hut also in those who have coronary spasm.

关 键 词：阿司匹林 抵克力得 血管痉挛 

分 类 号：R541.4[医药卫生—心血管疾病]