粘膜瓣防止气管瘢痕狭窄的实验研究  

An Experimental Study of Mucosal Flaps in Repairing Large Defect of Dogs' Tracheal Mucosa

作　　者：杨俊明[1] 迟汝澄[1] 

机构地区：[1]第四军医大学唐都医院耳鼻咽喉科

出　　处：《中华耳鼻咽喉科杂志》1994年第1期27-29,T006,共4页Chinese Journal of Otorhinolaryngology

摘　　要：本实验将１４只犬气管粘膜剥离后切去，制造面积为２０ｍｍ×２５ｍｍ的全层粘膜缺损面，随机分成两组：一组用松解后转移创缘粘膜处理创面，一组作为对照。通过大体、光镜及扫描电镜观察，并以碳粉作为示踪剂观察其在创面上的移动速度，对存活时间为１～１０周的两组创面修复速度、质量及瘢痕狭窄程度进行比较。结果表明：利用创缘粘膜转移能有效地加速创面的修复，减轻了瘢痕狭窄的形成。The tracheal mucosa of fourteen dogs was denuded and resected in sizes of 20mm × 25mm respectively.The raw surfaces were managed with mucosal flaps.The healing process of denuded area was observed by macroscope,light microscope and scanning electron microscope.Te outcomes were compared with those of control group.From this experiment it was demonstrated that the surgical ap-proach could effectively promote epithelial healing of denuded surfaces,prevent formation of cicatricial stenosis in trachea and get an excellent epithelization on the wounds.

关 键 词：气管狭窄 外科皮瓣 瘢痕 

分 类 号：R653[医药卫生—外科学]