Preparation and Evaluation of Molecularly Imprinted Monolithic Column for Felodipine in Micro-liquid Chromatography  

作　　者：QiLiangDENG ZhiHongLUN ChaoYAN RuYuGAO 

机构地区：[1]StateKeyLaboratoryofElementOrganicChemistry,InstituteofElementOrganicChemistry,NankaiUniversity,Tianjin300071 [2]UnimicroTechnologiesInc.,4713FirstStreet,Pleasanton,CA94566,USA [3]StateKeyLaboratoryofElementOrganicChemistry,InstituteofElementOrganicChemistry,NankaiUniversity,Tianjin300071／／I＇heSchoolofScience,UniversityofScienceandTechnologyofTianjin,Tianjin300222

出　　处：《Chinese Chemical Letters》2005年第7期955-958,共4页中国化学快报（英文版）

基　　金：This work was supported by the National Natural Science Foundation of China(20175010).

摘　　要：This study concentrated on the production of molecularly imprinted polymers (MIPs) as highly selective sorbents for felodipine (FLD), a representive dihydropyridine calcium antagonists. Demonstrated chromatographically through a selection factor, these MIPs showed high selectivity for the template molecule among a group of structurally similar compounds. The recognition was found to correlate with structural similarity to the template compound.

关 键 词：Molecularly Imprinted polymers felodipine. 

分 类 号：R972.4[医药卫生—药品]