Tei指数评价原发性高血压患者左室收缩及舒张功能的临床研究  

Estimation of Left Ventricular Global Function with Tei Index in Patients with Essential Hypertension

作　　者：于蕾[1] 任卫东[1] 李玉宏[1] 郑浩[1] 张东旭[1] 马春燕[1] 

机构地区：[1]中国医科大学附属第一医院心功能科,沈阳市110001

出　　处：《中国超声医学杂志》2005年第7期506-508,共3页Chinese Journal of Ultrasound in Medicine

摘　　要：目的探讨Tei指数评价原发性高血压患者左室收缩及舒张功能的临床价值。方法原发性高血压病患者65例,平均年龄(56.18±2.64)岁,均符合WHO关于原发性高血压病的诊断标准。将这65例患者分为3组:构型正常者为A组(32例);向心性肥厚者为B组(19例);离心性肥厚者为C组(14例)。正常对照组为D组(30例)。行常规超声心动图检查测量左室舒张末期内径(LVDd)和舒张末期左室壁相对厚度(RWT),二尖瓣口血流频谱舒张早期和舒张晚期血流峰值之比(E/A),E峰减速时间(DT),左室流出道血流频谱,左室射血分数(EF)以及Tei指数。结果A组、B组和C组的室间隔厚度较D组明显增厚,P值均<0.01;C组的LVDd较A组、B组和D组明显增大,P值<0.01;A组、B组和C组的E/A均较D组减小,P值均<0.01;C组的EF值比D组明显减小,P值<0.01;C组的Tei指数较D组明显延长,P值<0.01,A组和B组的Tei指数比D组也明显减小,P<0.05,并且A组和B组与C组相比同样具有统计学意义。结论Tei指数能够简单、敏感、准确、综合评价左室的收缩及舒张功能。Objective To investigate the value of a new index-Tei index for estimating left ventricular global function in patients with essential hypertension.Methods This study included 65 patients with essential hypertension divided into three groups:normal left ventricle ( group A,32 cases),concentric remodeling (group B,19 cases),eccentric remodeling (group C,14 cases),and 30 normal subjects as the control group.The conventional echo-Doppler parameters assessed included:The diastolic diameters of left ventricle (LVDd),RWT,E/A ratio,deceleration time (DT),ejection fraction (EF) and Tei index.Results RWT was increased in group A、B and C compared with group D,P< 0.01.LVDd in group C was larger than those of group A、B and D,P<0.01.E/A in group A、B and group C were all decreased compared with group D,P<0.01.The EF was significantly reduced in group C than that of group D,P<0.01.Tei index in group C was prolonged than that of group D,P<0.01.Conclusions Tei index was valuable and simple for estimating left ventricular systolic and diastolic functions with high sensitivity in hypertension patients.

关 键 词：原发性高血压患者 舒张功能 左室收缩 指数评价 临床研究 Tei指数 左室舒张末期内径 二尖瓣口血流频谱 原发性高血压病 超声心动图检查 高血压病患者 室壁相对厚度 左室射血分数 向心性肥厚 正常对照组 左室流出道 室间隔厚度 

分 类 号：R541.3[医药卫生—心血管疾病]