壳聚糖铜(Ⅱ)配位与氧化控制降解寡糖的GFC色谱研究  

Formation of Cu(Ⅱ) with Chitosan and the Study of GFC Spectra Study on the Mol ecular Weight Distribution of Oligosaccharides by Oxidizing Degradation

作　　者：陈祎平[1] 郝红元[1] 张岐[1] 葛庆凯[1] 王平红[1] 

机构地区：[1]海南大学海南省精细化工重点实验室,海南海口570228

出　　处：《光谱学与光谱分析》2005年第6期992-995,共4页Spectroscopy and Spectral Analysis

基　　金：国家自然科学基金(20361003);国家高技术研究发展专项(2002AA629130);海南省教育厅基金资助项目

摘　　要：在壳聚糖溶液中加入铜离子使形成壳聚糖铜配合物,通过IR ,UV ,元素分析及热重分析等对壳聚糖铜配合物进行表征。用H2 O2 对形成的壳聚糖Cu(Ⅱ)配合物进行氧化降解,测定了降解产物寡糖的平均数均分子量和分子量分布。结果表明壳聚糖铜配合物在升高温度时,在过氧化氢的存在下降解迅速,降解从大分子量范围开始,降解寡糖分子量分布在温度和降解时间相同条件下大大窄于目前常用的盐酸和纯过氧化氢氧化降解方法。分子量分布指数与降解寡糖的平均数均分子量有关,当高于10个寡聚糖数(DP)时,DP越小,分子量分布指数越小。Complexes of chitosan with Cu(Ⅱ) were prepared by adding Cu(OAc)_2·H_2O to c hitosan solution. IR, UV, elemental analysis, and thermal weight analysis were u sed to characterize the complex. The results showed that there were coordinate bands formed. H_2O_2 was used to degrade chitosan-Cu(Ⅱ) complex, and the mo lecular distribution of degraded products was investigated. The result suggeste d that the chitosan could be degraded rapidly, the degradation started from high er molecular weight range, and the molecular weight distribution of oligosacchar ides was much more narrow than that of degraded products with usual methods, suc h as hydrolysis acidic and oxidizing conditions. The index of molecular weight d istribution changed with the average degradability. When exceeding 10 oligosacch arides, the smaller the DP, the smaller the index.

关 键 词：壳聚糖 壳聚糖铜配合物 配位催化氧化 降解 

分 类 号：O657.7[理学—分析化学]