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机构地区:[1]重庆邮电学院,重庆400065
出 处:《重庆邮电学院学报(自然科学版)》2005年第4期511-515,共5页Journal of Chongqing University of Posts and Telecommunications(Natural Sciences Edition)
基 金:国家重点基础研究发展规划资助项目(G19999011708);国家自然科学基金资助项目(9002012)。
摘 要:综述了在离体实验条件下高等植物DNA解旋酶在以下多方面具有重要的生物学功能:包括DNA重组、DNA复制、翻译启始、rDNA转录及在pre-rRNA加工过程早期阶段,双链断裂修复、端粒长度维持、核苷酸切除修复、花发育中的细胞分裂/增殖、基因组甲基化方式保持、植物细胞周期和细胞基本生命活动的维持。最近玉米基因组中发现的解旋子(helitron)插入说明高等植物DNA解旋酶可能在植物生长与发育中有重要调控作用。因而有着重要的生物技术应用价值。DNA helicases are molecular driving proteins that open double-helixed structure transiently and play an important role in DNA metabolism.The helicases are known so far to share common features.The evidence shows that DNA helicases are at least involved in the biological processing as follows:DNA recombination,DNA replication,translation initiation,rDNA transcription,the early stage of pre-rRNA processing,double strand break repair,and cell division/propagation in the flower development and so on.The new discovery of helitron in maize genome further displays that DNA helicases must function in growth and development in higher plants. The field in botany has received little attention and one of the aims of this paper is to remind schsolar of this point.There is no doubt that this exciting frontier in higher plants will be changed greatly because of the wide prospective in regulating cellular machinery and biotechnological applications.
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