滋肾丸的质量标准研究  

Study on Quality Standards for Zishen Pill

作　　者：张秋红[1] 滕英博[1] 

机构地区：[1]中国人民解放军南京军区南京总医院制剂科,江苏南京210002

出　　处：《中国药业》2005年第7期31-32,共2页China Pharmaceuticals

摘　　要：目的:制订滋肾丸的质量控制标准。方法:采用薄层色谱法对制剂中的君药进行定性鉴别,采用紫外分光光度法对其中丹皮酚进行定量研究。结果:丹皮酚在3.6～8.4μg/mL范围内浓度与吸收度呈良好线性关系,r=0.9999,平均回收率为97.85%(n=6),RSD为3.93%。结论:该法稳定可靠,可作为滋肾丸的质量控制依据。Objective:To establish the quality control criteria for Zishen pill.Met hods:TLC method was employed to determine and differentiate the main drug of thi s pill,and UV spectrophotometry method was used to perform quantitative determin ation of paeonol in the pill. Results:The calibration curve for paeonol was line ar within the range of 3.6～8.4 μg/mL(r=0.999 9).The average recovery was 97.85 %(n=6) and the RSD was 3.93%.Conclusion:The method of determination is stable an d reliable and therefore can be used as the basis of quality control of Zishen p ill.

关 键 词：滋肾丸 薄层色谱法 丹皮酚 紫外分光光度法 

分 类 号：R286.0[医药卫生—中药学]