急性肺炎患儿腺苷脱氨酶活性观察  

STUDY ON ADENOSINE DEAMINASE ACTIVITY IN PATIENTS WITH ACUTE PNEUMONIA

作　　者：马珍奇[1] 赵英姿[1] 李丽琦 

机构地区：[1]西安医科大学第二附属医院,710004

出　　处：《中华儿童保健杂志》1994年第4期244-245,共2页

摘　　要：本文对30例急性肺炎患儿血腺苷脱氨酶(ADA)活性及血清免疫球蛋白(Ig)含量进行了观察.急性肺炎患儿ADA活性值(22.4±7.11u/ml)虽高于正常对照(19.6±3.64u/ml),但无显著差异.肺炎患儿IgA含量明显低于正常对照组,差异显著。16例IgA含量降低者中,14例(93.33％)ADA活性正常,仅2例(6.67％)活性<15u/ml(正常对照的最低测定值)。据此推测急性肺炎的发病基础可能与其免疫功能不足有关.而ADA活性在病程中并无明显改变,ADA活性对小儿急性肺炎的发生究竟起何作用,值得进一步研究。In the present study, the serum adenosine deaminase (ADA) activity and the immunoglobulin(Ig) content were investigated in thirty acute pneumonic infants. Although the patients'ADA activity was a little higher (22. 4±7. 11/ml) than the control(19. 6±3. 64u/ml)there was no significant difference between the two groups. IgA decreased markedly in the patient's serum as compared to the nomal control( P <0. 05). In the total sixteen cases whose serum IgA contents decreased greatly only two had lower ADA activities (15u/ ml below). This was the lowest point in the nomal control. From the above we deduce that there are some relationships between bronchopneumonia and immunodeficiency and that the role of ADA taken part in during the respiratory infaction period is still a secret which need further investigations in the future.

关 键 词：急性肺炎 腺苷脱氨酶 免疫球蛋白 儿童 

分 类 号：R725.631[医药卫生—儿科]