多巴胺在2-氨基-5-巯基-[1,3,4]三氮唑自组装膜电极上的准可逆行为研究及分析应用  

The Quasi-reversible Electrochemical Behavior of Dopamine and Its Application at a Self-assembled Monolayers Gold Electrode Modified with2-Amino-5-mercapto-[1,3,4]triazole

作　　者：刘传银[1] 周享春[2] 陆光汉[3] 

机构地区：[1]郧阳师范高等专科学校化学系,湖北丹江口442700 [2]长江大学化学工程系,湖北荆州434023 [3]华中师范大学化学学院,湖北武汉430079

出　　处：《分析测试学报》2005年第4期13-16,共4页Journal of Instrumental Analysis

基　　金：湖北省教育厅重点资助项目(2003A010)

摘　　要：利用新合成的巯基试剂2-氨基-5-巯基-[1,3,4]三氮唑在金电极表面进行了首次自组装,用电化学法和扫描电子显微镜对自组装膜电极进行了表征。研究了多巴胺在该自组装膜电极上的电化学行为,发现该自组装膜能有效促进多巴胺在电极与溶液之间的电子传递,表现为二电子传递的准可逆行为,电极反应速率常数为0.105cm/s。该自组装膜电极用于多巴胺注射液含量的测定,结果满意。Anewly synthesized reagent2-amino-5-mercapto-[1,3,4]triazole was used to fabricate self-assem-bled monolayers(SAMs)on gold for the first time.The SAMs modified electrode was characterized by electro-chemical methods and scanning electronic microscopy(SEM).The electrochemical behaviors of dopamine were investigated at the SAMs electrode.The experimental results showed that the electrochemical oxidation of dopamine was a quasi-reversible behavior involving two-electron transfer,and the electron transfer rate was0.105cm/s.The SAMs electrode has been used to determine the content of dopamine in drug injections with satisfactory results.

关 键 词：2-氨基-5-巯基-[1 3 4]三氮唑 多巴胺 自组装膜 准可逆行为 

分 类 号：O657.1[理学—分析化学]