肝泰乐在尘肺预防性抗痨过程中的保肝作用及经济学分析  

Liver Protection Effect of Glucurolactone in the Course of Preventive Anti-tuberculosis of Pneumoconiosis

作　　者：王雪涛[1] 张建芳[1] 李云[1] 

机构地区：[1]煤炭工业职业医学研究所,北京市102300

出　　处：《职业与健康》2005年第8期1123-1124,共2页Occupation and Health

摘　　要：目的探讨肝泰乐在尘肺预防性抗痨过程中的保肝效果及其经济学意义。方法①从2131份病历中筛选出482份曾进行过抗痨治疗的病历,其中337例用肝泰乐保肝,145例未用保肝药,对两组的肝功异常率进行统计学分析比较。②出现肝功异常后用益肝灵治疗3个月,此治疗方案与前两个方案进行经济学比较。结果①在尘肺预防性抗痨过程中,用肝泰乐与不用肝泰乐肝毒性出现的概率差异具有非常显著性(P<0·01),肝泰乐用于尘肺预防性抗痨具有明显的保肝作用。②3种治疗方案进行经济学比较结果加用肝泰乐保肝是最佳方案。结论肝泰乐用于煤工尘肺预防性抗痨中的保肝是有效的,而且是经济的。Objective To explore the liver protection effect of Glucurolactone in the course of preventive anti-tuberculosis of pneumoconiosis and its financial significance. [Methods] 482 cases who had received anti-tuberculosis treatment were selected and divided into two groups, namely the Glucurolocatone group with 337 cases and the control group with 145 cases. Statistical contrast was made on the abnormal rate of the liver function of the two groups. 3 months treatment with Yiganling was conducted on the cases that were found with abnormal liver function. Financial contrast was made between different groups. [Results] Significant difference was found between the Glucurolocatone group and the control group (P<0.01). Glucurolocatone has obvious liver protection effect in the course of preventive anti-tuberculosis of pneumoconiosis. The financial contrast indicated that the best method among the 3 was the one using Glucurolocatone to protect the liver. [Conclusion]The method of using Glucurolocatone to protect the liver is proved to be effective and economical in the course of preventive anti-tuberculosis of pneumoconiosis.

关 键 词：尘肺 肝泰乐 抗痨 保肝 经济学 

分 类 号：R181.3[医药卫生—流行病学]