肝癌经皮门静脉时辰化疗的疗效观察  

Purcutaneous Portal Vein Chronomodulated Chemotherapy on Treatment of Liver Cancer

作　　者：李凌[1] 吴建兵[1] 兰琼玉[1] 徐华[1] 冯龙[1] 王顺金[1] 黄平[1] 

机构地区：[1]江西医学院第二附属医院肿瘤科,江西南昌330006

出　　处：《实用临床医学（江西）》2005年第7期23-24,共2页Practical Clinical Medicine

基　　金：江西省科委课题(20041B0303100)

摘　　要：目的探讨不能手术切除的中晚期肝癌的治疗新途径。方法对18例肝癌患者在TACE治疗后再经皮穿剌门静脉置管,采用微电脑控制的全自动注药盒每天在特定的时间向门静脉内注入DDP及以正弦曲线速率注入5Fu进行时辰化疗,对生存时间进行观察比较。结果生存期延长;AFP阳性病人的肿瘤标记物AFP大幅度下降;3例门静脉癌栓病人有2例癌栓消失。结论门静脉置管时辰化疗联合TACE治疗中晚期肝癌疗效较为满意。Objective:To explore a new therapeutics on patients with un ab le surgical excisional advanced liver cancer.Metheds:After TACE treatment,18 pat ients with advanced liver cancer were treated by means of the portal vein chrono modulated chemotherapy by which DDP and 5-Fu was infused into the portal vein through the inserted catheter;survival was observed.Results:Survival period was longer;AFP was reduced remarkable;carcinous thrombus in the master portal v ein was missed on two patients among three.Conclusion:It is demonstrated that po rtal vein chronomodulated chemotherapy combined with TACE on treatment of liver cancer is an effective therapy.

关 键 词：肝肿瘤 门静脉 时辰化疗 

分 类 号：R735.7[医药卫生—肿瘤]