三七总苷注射液辅助治疗早期糖尿病肾病患者的疗效观察  

A Clinical Study the Effect of Panax Notoginseng Saponins(PNS) on Incipient Diabetic Nephropathy

作　　者：张征宇[1] 孙澍彬[1] 

机构地区：[1]广东省东莞市石龙人民医院,东莞523321

出　　处：《中国中西医结合肾病杂志》2005年第7期407-409,共3页Chinese Journal of Integrated Traditional and Western Nephrology

基　　金：东莞市科技局科研基金资助项目(No.200354)

摘　　要：目的观察三七总苷注射液辅助治疗早期糖尿病肾病患者的疗效。方法选择早期糖尿病肾病患者66例,随机分为治疗组和对照组,均给予饮食控制、降血脂治疗及控制血糖;治疗组则增加三七总苷注射液,15d为1疗程,共2个疗程,每个疗程间隔2d。同时观察比较治疗前后患者血、尿β2-微球蛋白(β2-MG),尿微量蛋白(Alb),尿蛋白(PRO)定量定性等指标的变化。结果治疗组总有效率(84.8%)优于对照组(63.6%)(P<0.05);此外,治疗组患者血β2-MG及尿β2-MG、Alb、PRO定量定性治疗前后均有明显下降且优于对照组;治疗过程中尚未发现副作用及严重的不良反应。结论三七总苷注射液可有效改善糖尿病肾病患者的肾功能。Objective:To observe the efficacy of Panax notoginseng saponins (PNS) on incipient diabetic nephropathy.Methods:66 cases with incipient diabetic nephropathy were divided into two groups at random. The combined therapy with PNS was gave to treatment group (33 cases). Combined therapy was only gave to control group (33 cases).Results:The counts of ALB,β_2-MG of blood and urine, urine protein of treatment group were descented obviously after treatment. The clinical total effective rate of treatment group (84.8%) was outstripped the Control group(63.6%) (P<0.05). None grave side effectd and manifested during the treatment.Conclusion:PNS can improve the renal function in the patients with incipient diabetic nephropathy effectively.

关 键 词：糖尿病肾病患者 三七总苷 治疗早期 注射液 疗效观察 尿Β2-微球蛋白 尿Β2-MG 血Β2-MG 治疗前后 定量定性 降血脂治疗 尿微量蛋白 治疗组 对照组 饮食控制 控制血糖 观察比较 总有效率 不良反应 治疗过程 疗程 尿蛋白 

分 类 号：R587.2[医药卫生—内分泌]