高氧血颈动脉灌注治疗重型颅脑损伤  

Perfusion of highly oxygenated blood into carotid arteries in the treatment of s evere craniocerebral trauma

作　　者：陈东[1] 戴黎萌[1] 蔡坤皓[1] 万勇[1] 陈建良[1] 吴耀晨[1] 徐如祥[2] 

机构地区：[1]暨南大学医学院第二附属医院深圳市人民医院神经外科,518020 [2]南方医科大学珠江医院神经外科,广州510282

出　　处：《中华神经医学杂志》2005年第7期698-700,共3页Chinese Journal of Neuromedicine

基　　金：深圳市科委自然科学基金(200204015)

摘　　要：目的研究高氧血颈动脉灌注在重型颅脑损伤治疗中的作用。方法对22例重型颅脑损伤患者于伤后约3.5d行高氧血颈动脉灌注治疗,监测灌注前、中、后的PbtO2、PbtCO2、pHbt值变化以及伤后三月格拉斯哥预后评分(GOS)的变化。结果高氧血颈动脉灌注能改善重型颅脑损伤后早期继发性脑缺血缺氧状态和意识状态,进而改善患者预后。结论高氧血颈动脉灌注在重型颅脑损伤的早期治疗中起着积极和重要的作用。Objective To study the effect of perfusing highly oxygenated blood into carotid arteries in the treatment of severe head injury. Methods Highly oxygenated blood was perfused into carotid arteries of 22 patients with severe head injure at about 3.5 d after accident and PbtO2?PbtCO2?pHbt value wa s monitored before, during and after the treatment, and Glasgow Outcome Scale (G OS) of the patients in three months after injury was also observed. Results The perfusion of highly oxygenated blood into carotid arteries can improve the state of early secondary cerebral ischemia and hypoxia, consciousness after inj ury and finally make better the outcome of the patients. Conclusion The in fusion of highly oxygenated blood into carotid arteries plays an active and impo rtant role in the early treatment of severe head injury.

关 键 词：高氧血 颅脑损伤 血液灌注 

分 类 号：R651[医药卫生—外科学]