稀土暴露对儿童智商的影响  

Effects of Thulium Exposure on IQ of Children

作　　者：范广勤[1] 郑辉烈[1] 袁兆康[1] 

机构地区：[1]江西医学院公共卫生学院,江西南昌330006

出　　处：《环境与健康杂志》2005年第4期256-258,共3页Journal of Environment and Health

基　　金：国家自然科学基金资助项目(39869003);江西省自然科学基金资助项目(0100005)

摘　　要：目的探讨稀土暴露与儿童智商的关系。方法采用绘人智能法对江西省某稀土矿区(暴露组,n=229)和对照区(对照组,n=235)7～10岁儿童进行智商测定,并使用电感耦合等离子体质谱法(ICP-MS)测定暴露组(n=69)和对照组(n=43)儿童静脉血稀土浓度,同时对儿童稀土暴露与智商的关系进行多元逐步回归分析。结果儿童血中15种稀土元素均可检出,且暴露组儿童血总稀土浓度(2.18±1.08)ng/g,比对照组(1.26±0.35)ng/g高出0.73倍,差异有统计学意义(P<0.01)。暴露组儿童智商犤(82.63±12.16)分犦低于对照组犤(87.08±15.28)分犦,差异有统计学意义(P<0.01)。多因素分析显示,家与稀土矿区距离及家中是否堆放稀土均可影响儿童智商水平。结论稀土暴露对儿童智商有一定的影响。Objective To study the effects of environmental exposure to rare earth elements REEs on intelligence of children. Methods Intelligence quotient IQ were examined with Drawing a Man Test in 464 children aged 7-10 years living in RE ore containing area and the control area in Xunwu country Jiangxi province China. Fifteen kinds of REEs in 112 blood samples 69 samples from RE ore area and 43 samples from the control area  were detected by inductively coupled plasma source mass spectrometry ICP-MS. Results All 15 kinds of REEs were detected in each sample the content of blood REEs of the children in the rare earth area 2.18±1.08 ng/g was 1.73 times of that of the children in the control area 1.26±0.35 ng/g the difference was significant P<0.01. The score of IQ in the exposure group 82.63±12.16 was significantly lower than that in the control 87.08±15.28 and the percentage of high IQ decreased and the percentage of low IQ increased . Multiple regression analysis showed that the distance from home to the RE ore and piling up RE in house were related to the score of children’s IQ. Conclusion REEs exposure may be related to children’s IQ decreasing.

关 键 词：稀土元素 环境暴露 儿童 

分 类 号：R339.3[医药卫生—人体生理学] R994.6[医药卫生—基础医学]