Mass Spectrometry of 2a,4-Disubstituted 5-Benzoyl-2a,3,4,5-tetrahydro-2-phenoxy-azeto[1,2-a][1,5]benzodiazepin-1(2H)-ones Under Electron Impact Ionization Conditions  

作　　者：XUJia-xi HUANGXu 

机构地区：[1]KeyLaboratoryofBioorganicChemistryandMolecularEngineeringofMinistryofEducationofChina,DepartmentofChemicalBiology,CollegeofChemistryandMolecularEngineering,PekingUniversity,Beijing100871,P.R.China

出　　处：《Chemical Research in Chinese Universities》2005年第4期452-456,共5页高等学校化学研究（英文版）

基　　金：SupportedbytheNationalNaturalScienceFoundationofChina(Nos.20272002and20472005),theExcellentYoungTeachersProgram,theScientificResearchFoundationfortheReturnedOverseaChineseScholarsofMinistryofEducationofChina,andthePresidentGrantofPekingUniversity.

摘　　要：The mass spectrometric fragmentation of 2a,4-disubstituted 5-benzoyl-2a,3,4,5-tetrahydro-2-phenoxy-azeto{[1,2-a]}[1,5]benzodiazepin-1(2H)-ones has been investigated by means of mass-analyzed ion kinetic energy spectrometry under electron impact ionization conditions. All compounds tend to lose different moieties, such as phenoxy, phenoxy and H, and phenoxyketene. Both [M +-PhO] and [M +-PhOH] ions could further lose CO, and the [M +-PhOCHCO] ions could lose propene or styrene, PhCON, PhCOHN, and other fragments.The mass spectrometric fragmentation of 2a,4-disubstituted 5-benzoyl-2a,3,4,5-tetrahydro-2-phenoxy-azeto{[1,2-a]}[1,5]benzodiazepin-1(2H)-ones has been investigated by means of mass-analyzed ion kinetic energy spectrometry under electron impact ionization conditions. All compounds tend to lose different moieties, such as phenoxy, phenoxy and H, and phenoxyketene. Both [M +-PhO] and [M +-PhOH] ions could further lose CO, and the [M +-PhOCHCO] ions could lose propene or styrene, PhCON, PhCOHN, and other fragments.

关 键 词：Azeto[1 2-a][1 5]benzodiazepin-1(2H)-one Mass spectrometry FRAGMENTATION Mechanism 

分 类 号：O625.42[理学—有机化学] O657.63[理学—化学]