中等负荷运动训练对心理应激大鼠行为和氧自由基的影响  

The effect of moderate exercise on the behaviors and the free radical in peripheral blood of SD rats after being received noise stress

作　　者：陈爱国[1] 颜军[1] 

机构地区：[1]扬州大学体育学院,扬州225002

出　　处：《中国行为医学科学》2005年第7期582-583,共2页Chinese Journal of Behavioral Medical Science

基　　金：江苏省教育厅自然科学研究指导性项目(IK0310064)

摘　　要：目的研究中等负荷的运动训练对心理应激大鼠行为和外周血氧自由基的影响。方法健康的雄性SD大鼠32只,随机分为对照组、心理应激组、运动组和运动心理应激组,实验后测定大鼠的开场行为以及外周血自由基的变化情况。结果①心理应激组、运动组以及运动心理应激组(分别为64.37±16.90,59.63±13.45,54.88±10.68)与对照组(43.25±16.42)比较数都有显著的增加(P<0.05);伸高次数(分别为16.63±5.09,10.00±6.85,17.00±10.77)与对照组(23.88±6.79)相比较都有所降低,且心理应激组和运动组具有显著的统计学意义(P<0.05)②心理应激组、运动组(分别为78.13±18.10和56.48±19.21)与对照组(36.90±4.19)比较SOD的活性显著增强(P<0.05),运动心理应激组SOD的活性(36.90±4.19)降低;而MDA浓度的变化,心理应激组(8.63±3.18)与对照组(4.90±1.58)比较显著增加(P<0.01),运动组(2.76±1.60)显著降低(P<0.01),运动心理应激组下降但差异无显著性。结论中等负荷的运动训练可以通过降低心理应激反应的强度,拮抗心理应激对机体的损伤。ObjectiveTo investigate the effect of moderate exercise on the free radicals in peripheral blood of SD rats after being received noise stress. MethodsThirty two health male SD rats were divided into four groups. one as controlled group, one only getting psychological stress, one receiving swimming training for 60mins, one receiving swimming training for 60 mins and psychological stress. The open-field test,SOD activity and the MDA content in peripheral blood of SD rats were determined. Results①Compared with C group(43.25±16.42), the numbers of crossing in P、S and PS group (64.37±16.90,59.63±13.45,54.88±10.68)were significantly higher( P <0.05);the numbers of rearing in P,S and PS group(16.63±5.09,10.00±6.85,17.00±10.77) were lower than that in C group(23.88 ±6.79 ), furthermore;the numbers of rearing in P and S group were significantly decreased.②Compared with C group(36.90±4.19),the SOD activity in P and S group(78.13±18.10 and 56.48±19.21) were significantly higher( P < 0.05 );the SOD activity in PS were lower.Compared with C group(4.90±1.58),the MDA concentration in P group were significantly increased, while the MDA concentration in S group were significantly decreased, however, the MDA concentration in PS group were lower but not significantly.ConclusionThe moderate exercise maybe bring down the intensity of stress reaction to depress the effect of the noise stress in SD rats.

关 键 词：运动训练 氧自由基 大鼠行为 负荷 中等 心理应激反应 对照组 运动组 SD大鼠 变化情况 血自由基 开场行为 SOD 外周血 统计学 MDA 显著性 活性 

分 类 号：G804[文化科学—运动人体科学]