微循环研究常用部位的肽能和胺能神经支配  

THE PEPTIDERGIC AND SEROTONINERGIC INNERVATION IN THE REGIONS COMMONLY USED FOR MICROCIRCULATION STUDIES

作　　者：张励才[1] 王梅申[1] 朱治远[1] 张凤真[1] 

机构地区：[1]徐州医学院神经解剖学研究室

出　　处：《中国应用生理学杂志》1995年第2期133-136,共4页Chinese Journal of Applied Physiology

摘　　要：以逆行追踪与免疫细胞化学相结合法，探讨了大鼠提睾肌、盲肠系膜和耳廓等微循环研究常用部位的神经肽Ｙ（ＮＰＹ）、降钙素基因相关肽（ＣＧＲＰ）、甲啡呔（Ｍ－ＥＮＫ）和５－羟色胺（５－ＨＴ）等肽能和胺能神经的支配。结果表明：支配提睾肌的运动和感觉神经元分别含有５－ＨＴ和ＣＧＲＰ。支配提睾肌血管、盲肠系膜及其血管的交感节神经元，一部分含有ＮＰＹ，一部分含有Ｍ－ＥＮＫ；支配耳廓局部的运动和感觉神经元均含有ＣＧＲＰ，而支配该部的交感节后神经元则分别含有ＮＰＹ、ＣＧＫＰ和５－ＨＴ。上述结果提示：提睾肌、盲肠系膜和耳廓局部除受经典递质的神经支配之外，ＮＰＹ、ＣＧＲＰ、Ｍ－ＥＮＫ和５－ＨＴ等也同样参与了上述各部位的运动、感觉以及自主性功能的调节活动。The peptidergic(NPY,CGRP,M- ENK)and serotoninergic innervations in the cremaster muscle,mesocecum and auricle were studied with subunit B of cholera toxin horseradish peroxidase(CB-HRP)combined with peroxidase antiperoxidase complex (PAP)method.The re- sults were as follows:Some motor neurons of the cremaster muscle showed 5-HT immunoreactivity(5-HTir)and the sensory neurons showed CGRPir. Some sympathetic postganglionic neurons innervating the cremaster blood vessels showed NPYir and M-ENKir. Some sympathetic postganglionic neurons innervating the mesocecum and its blood vessels showed NPYir and M-ENKir. Both motor and sensory neurons innervating the auricle showed CGRPir.Their sympathetic postganglionic neurons showed 5-HTir,CGRPir or NPYir. The physiological significance of NPY,CGRP,M-ENK and 5-HT in microcirculation is discussed.

关 键 词：提睾肌 盲肠系膜 耳廓 微循环 神经支配 

分 类 号：R331.35[医药卫生—人体生理学]