复方一枝蒿颗粒剂的体外抗菌作用  

Antibacterial activity of compound Yizhihao particles in vitro

作　　者：张炳华[1] 王亚男[1] 张彦琼[2] 

机构地区：[1]新疆医科大学病原生物学教研室,新疆乌鲁木齐830054 [2]中南大学卫生部纳米重点实验室,湖南长沙410078

出　　处：《中国现代医学杂志》2005年第13期1968-1969,共2页China Journal of Modern Medicine

摘　　要：目的检测复方一枝蒿颗粒剂的体外抗菌作用。方法采用MH(Mueller-Hamilton)肉汤和MH营养琼脂平板倍比稀释培养法。结果复方一枝蒿颗粒剂对金黄色葡萄球菌的最小抑菌浓度(MIC)为1∶16,最小杀菌浓度(MBC)为1∶8;肺炎链球菌的MIC为1∶16,MBC为1∶8;乙型溶血性链球菌的MIC为1∶8,MBC为1∶4;大肠埃希菌的MIC≤1∶2MBC≤1∶2。结论复方一枝蒿颗粒剂对金黄色葡萄球菌、乙型溶血性链球菌和肺炎链球菌有明显抑制作用。[Objective] To study the antibacterial activity of the Compound YiZhiHao particles in vitro. [Methods] The culture of MH broth and MH agar plate with 2-fold dilutions of the drug. [Results] The minimal inhibitory concentration of Compound YiZhiHao particles on staphylococcus aureus, pneumococcus, β-hemolytic streptococcus and escherichia coli were 1∶16, 1∶16, 1∶8 and 1∶2, respectively. The minimal bactericidal concentration were 1∶8, 1∶8, 1∶4 and 1∶2, respectively. [Conclusion] The Compound YiZhiHao particles have obvious antibacterial activity to the staphylococcus aureus, β-hemolytic streptococcus and pneumococcus.

关 键 词：复方一枝蒿颗粒剂 体外抗菌作用 

分 类 号：R915[医药卫生—微生物与生化药学]