纳米羟基磷灰石与牙无机质的比较研究  

Comparison of compositional and structural characterizations of synthetic nano-hydroxyapatite and mineral phase from human teeth

作　　者：韩纪梅[1] 李玉宝[1] 梁新杰[2] 张利[1] 杨维虎[1] 莫利蓉[1] 周少雄[2] 

机构地区：[1]四川大学纳米生物材料研究中心四川大学分析测试中心 [2]钢铁研究总院安泰科技股份有限公司,北京100081

出　　处：《功能材料》2005年第7期1069-1071,共3页Journal of Functional Materials

基　　金：国家高新技术研究发展计划(863计划)纳米材料专项基金资助项目(2002AA302205)

摘　　要：用水热合成法制备了纳米磷灰石晶体。用透射电镜(TEM)、X射线衍射(XRD)、傅立叶-红外光谱(FT-IR)、等离子发射光谱(ICP)和X光电子能谱(XPS)分析和表征了纳米羟基磷灰石(n-HA)和牙磷灰石的组成、结构和形貌。结果表明用水热合成法制备的纳米磷灰石晶体有与牙无机质十分类似的组成、结构和形貌,同样含有羟基、碳酸根和钠离子。从仿生学角度出发,在制备纳米羟基磷灰石的过程中,应适当引入CO32-、F-以利于更好地模仿自然牙的组成,制备出高性能的n-HA与高分子或牙科树脂复合材料。Nano-apatite crystals was made from hydrothermal treatment. The crystal morphology and composition of the synthesized nano-HA were investigated using TEM, IR, XRD, ICP and XPS techniques and were also compared with those of human posterior teeth. The results indicate that nano-apatite crystals have a similar composition, crystal structure, morphology, crystalinity to that of human teeth, and also containing OH-, CO32-, Na-. From the view of biomimesis, the above ions or groups should be introduced to the nano-apatite to mimic the biological apatite as much as possible. Those analysis provide a promising perspective for further n-HA/dental resin composites preparation.

关 键 词：纳米磷灰石晶体 牙无机质 组成 结构 形貌 

分 类 号：R318.08[医药卫生—生物医学工程]