真菌降脂素治疗脂质代谢紊乱的临床研究  

Clinical Study on Fungus Lipid-Reducing Capsule in Regulating Lipometabolic Disorder

作　　者：林求诚[1] 叶盈[1] 方素钦[1] 王耀华[1] 沈宗国[1] 

机构地区：[1]福建省中医药研究院,福建医学院附属第一医院,福建省人民医院

出　　处：《中国中西医结合杂志》1995年第5期281-283,共3页Chinese Journal of Integrated Traditional and Western Medicine

摘　　要：１４０例患者随机分为真菌降脂素治疗组与山楂精降脂片对照组各７０例，另设真菌降脂素扩大治疗组９０例。结果：治疗组与对照组胆固醇（ＴＣ）、甘油三酯（ＴＧ）含量均明显下降，但治疗组下降的幅度大于对照组（Ｐ＜０．０５）；ＨＤＬ－Ｃ含量两组皆有上升，但治疗组上升的幅度大于对照组（Ｐ＜０．０５），提示本品的调脂疗效优于对照药物。治疗组高ＴＣ血症３８例，显效１６例，有效１６例，总有效率８４％；高ＴＧ血症５６例，显效２３例，有效２４例，总有效率８４％；低ＨＤＬ－Ｃ血症２６例，显效１２例，有效６例，总有效率６９％。治疗组的血液流变学指标得到明显改善。中医证候疗效表明，真菌降脂素有健脾祛湿、滋养肝肾的功效。结合安全性观测，表明该药是有效而安全的调脂药物。The patients with lipometabolic disorder were randomly divided into control group(70 cases),Fungus.Lipid-reducing Capsule(FLC)treated group(70 cases),augmented treated group (90cases).The results shown that:(1)TC and TG were reduced markedly in all three groups. The reducing extent in the treated group was greater than that in the control group (P<0.01).HDL-C was increased markedly in all three group.The increasing extent in the treated group was greater than that in the control group(P<0.05).These results indicated that the effectiveness of FLC was higher than that of control drug in the treatment of hyperlipidemia.(2)FLC had obvious effect in improving hemorheology indexes. (3) The therapeutic effect of TCM Syndrome-tape indicated that FLC could activate the Spleen, remove Dampness and nourish the Liver and Kidney.

关 键 词：真菌降脂素 脂质代谢紊乱 高胆固醇血症 

分 类 号：R589.205[医药卫生—内分泌]