4种植物多糖对S＿（180）细胞膜磷脂酰肌醇转换的影响  

Effect of Plant Polysaccharides on PhosphatidylinositolTurnover of Sarcoma S_(180) Cell Membranes

作　　者：黄添友[1] 佟丽[1] 李吉来[1] 梁谋[1] 吴波[1] 梁念慈[1] 

机构地区：[1]第一军医大学中西医结合研究所,广东医学院生化教研室

出　　处：《中国中药杂志》1995年第11期692-693,共2页China Journal of Chinese Materia Medica

基　　金：全军青年科学基金

摘　　要：将４种植物多糖分别于Ｓ＿（１８０）细胞膜，［ｒ－￣（３２）Ｐ］ＡＴｐ一同温育，抽提并分离肌醇磷脂进行放射自显影和液闪计数。实验结果表明茯苓多糖（ＰＰＳ），刺五加多糖（ＡＳＰＳ）具有抑制磷脂酰肌醇（ＰＩ）转换作用，而银耳多糖（ＴＦ）、香菇多糖（ＬＥＮ）无抑制作用。Mica sarcoma S_(180) cell membranes, [r-￣(32) P] ATP and plant polysaccharides (PPS, ASPS. TF andlentinan)were incubated together for 5 min at 30℃. Phosphatidylinositides were isolated and subjected to cintillationfluid counting. The results showed that PPS and ASPS, especially the latter, could inbibit the phosphatidyinostolturnover obviously ,while TF and lentinan had no such effect.

关 键 词：植物多糖 肿瘤 细胞膜 肌醇磷脂 

分 类 号：R285[医药卫生—中药学]