瑞香素及其铜（Ⅱ）、锌（Ⅱ）配合物对超氧自由基的清除作用  

Scavenging Effects of Daphnetin and Its Cu, Zn Complexes on superoxide Radical

作　　者：胡道道[1] 房喻[1] 崔亚丽[1] 孙作民[1] 

机构地区：[1]陕西师范大学化学系

出　　处：《中国中药杂志》1995年第12期749-750,共2页China Journal of Chinese Materia Medica

摘　　要：以健康人血红细胞及细胞膜为实验材料，利用核黄素－蛋氨酸光照体系产生Ｏ＿２，考察了瑞香素及其铜（Ⅱ）、锌（Ⅱ）配合物对ｏ＿２的清除作用，以铜（Ⅱ）配合物活性最高。ＳＯＤ、瑞香素及其铜（Ⅱ）、锌（Ⅱ）配合物对膜中过氧化脂质的产生均有一定的抑制作用。其中以ＳＯＤ活性最高。The scavenging effects of daphnetin (D) and its Cu ,Zn complexes on superoxide radical (O) gener-ated through the photooxidation of riboflavin were studied with human red blood cells (RBC) and RBC membrane asexperimental material. The Cu(Ⅱ) complex showed the highest activity. SOD, D and its Cu ( Ⅱ) ,Zn ( Ⅱ ) complexeswese found to have inhibitory effect on the production of lipid peroxide in the membrane ,SOD being the best amongthem.

关 键 词：瑞香素 配合物 超氧自由基 过氧化脂质 

分 类 号：R284.1[医药卫生—中药学]