颈椎退变性眩晕患者的血液流变学变化及加味补阳还五汤对其治疗作用的研究  

Studies on Changes of Hemorheology in Patients with Dizziness of Vertebae Cervical Degeneration and Role of“Modifical Bu Yang Huan Wu Decoction”in Ttreating.

作　　者：陈健[1] 金忠棋[1] 周君富[1] 周游[1] 

机构地区：[1]浙江医科大学附属第二医院

出　　处：《中国中医骨伤科》1995年第1期4-9,共6页Chinese Journal of Traditional Medical Traumatology & Orthopedics

摘　　要：本文随机选择了８０例经Ｘ线片和临床确诊的颈椎退变性眩晕患者以及与患者的年龄和性别相配对的８０例健康成年人作配对设计对照，进行了红细胞压积、红细胞沉降率、红细胞沉降率方程Ｋ值、血浆纤维蛋白原含量、血浆粘度、以及４ｓ（－１）、ｌ０ｓ．（－１）、２０ｓ．（－１）、４０ｓ．（－１）、１００ｓ．（－１）、２００ｓ．（－１）、切变率时全血表现粘度、红细胞电泳时间、血小板电泳时间值等血液流变学多项指标的检测。实验结果表明，与对照值相比较，患者组的红细胞压积、血浆纤维蛋白原含量、血浆粘度、各切变率时全血表观粘度、红细胞电泳时间、血小板电泳时间平均值均显著升高（Ｐ＜０．００１～０．０１），红细胞沉降率、红细胞沉降率方程Ｋ值平均值显著降低（Ｐ＜０．００１）。于８０例患者中随机选择了３３例患者，口服加味补阳还五汤２０～３０剂后进行上述血液流变学各项指标复查，结果表明：３３例患者服用加味补阳还五汤后的红细胞压积、血浆纤维蛋白原含量、血浆粘度、各切变率时的全血表观粘度、红细胞电泳时间、血小板电泳时间平均值均显著低于服药前（Ｐ＜０．００１～０．０２），红细胞沉降率、红细胞沉降率方程Ｋ值平均值皆显著高于服药前（Ｐ＜０．００１）。同时，临?The results of detecting HCT, ESR, ESRK, FBG, plasma viscosity, whole blood apparent visosites at shear rate of 4s.-1￣20s.-1,and erythrocyte electrophoresis time(EET),platelet electrophoresis time(PET)of 80 patients with dizziness of vertebae cervical degeneration and 80 healthy subjects showed that HCT,FBG, plasma viscosity, whole blood apparent viscosity, EET and PET velues of the patient group were significantly higher than those of the control group(P<0.001￣0.01),ESR and ESRK velues of the patient group were signficantly lower than those of the control group(P<0.001);that afterreceiving“Modifical Bu Yang Huan Wu Decoction,”HCT,FBG, plasma viscosity, whole blood apparent viscosity, EET, PET velues of 33 patients significantly lowered(P<0. 001￣0.02),ESR and SERK velues significantly increased (P<0. 001). It indicated that the changes of hemorrheology is one of the major reasons for diziness of vertebae cervical degeneration.

关 键 词：颈椎退变性 眩晕 血液流变学 补阳还五汤 

分 类 号：R255.305[医药卫生—中医内科学] R289.5[医药卫生—中医学]