黄芪佐治预防小儿原发性肾病综合征复发的初步研究  

The Preliminary Study of Astragalus on Preventing Children′s Initiate Nephropathy Syndrome Prelaps

作　　者：唐建华[1] 朱光华[2] 方明俊[2] 俞全胜[2] 

机构地区：[1]上海职工医学院,上海市200237 [2]上海市儿童医院

出　　处：《中国全科医学》2005年第14期1136-1137,共2页Chinese General Practice

基　　金：美国卫生基金提供资助(PSBH-Ⅳ-003)

摘　　要：目的观察黄芪在预防小儿原发性肾病综合征复发中的作用。方法将76例原发性肾病综合征患儿随机分为对照组和观察组,两组均常规应用泼尼松和潘生丁,观察组加用黄芪,随访12～24个月。结果治疗前两组患儿的IgA、IgM、IgG和CD+4/CD+8间差别均无显著性意义(P>0.05),治疗后除IgM外,IgA、IgG、CD+4/CD+8间差别均有显著性意义(P<0.05);两组患儿的复发率间差别有显著性意义(P<0.05)。结论在常规应用激素和口服潘生丁的基础上,加用黄芪对预防小儿原发性肾病综合征复发有一定的效果。Objective To observe the curative effect of astragalus on preventing the relapse of child initiate nephropathy.Methods 76 children who all suffered from the Initiate nephropathy were randomly allocated two groups.One is the control group including 41 children,only taking oral prednisone and persantine.The other is the intervention group including 35 children who take astragalus besides prednisone and persantine.They were medical observed in next 12～24 months.Results There is no obvious significance among IgA,IgM,IgG nd CD4/CD8 in the two groups before the treatment.After the treatment,there is significant difference in relapse rate of the two groups.Conclusion Astragalus with prednisone and persantine has some curative effect on preventing the relapse of child initiate nephropathy.

关 键 词：肾病综合征 复发 泼尼松 黄芪 

分 类 号：R692[医药卫生—泌尿科学]