激光多普勒测量后半规管壶腹嵴血流  

Observation of Cristae of Posterior Ampullae with Laser Doppler

作　　者：李学佩[1] 马芙蓉[1] 王伟[1] 

机构地区：[1]北京医科大学第三临床医院耳鼻咽喉科

出　　处：《中华耳鼻咽喉科杂志》1995年第4期230-232,共3页Chinese Journal of Otorhinolaryngology

基　　金：卫生部科学基金

摘　　要：建立测定前庭血流的方法学是研究前庭微循环的关键。应用激光多普勒血流计测定１０只豚鼠的后半规管壶腹嵴血流。结果：耳蜗血流为３１８．３９±９１．６６ｍＶ，后半规管壶腹嵴血流为１９４．００±４５．２６ｍＶ，在测定过程中血压稳定在９．９９～１０．２７ｋＰａ。前庭和耳蜗血流分别占内耳血流的３７．８６％和６２．１４％，前庭血流约为耳蜗血流的二分之一。可以认为，后半规管壶腹嵴血流在一定程度上反映前庭血流变化。激光多普勒具有连续、动态、实时、直接观察、且能重复的优点。To set up the methodology of measuring vestibular blood flow was the key to the study of vestibular microcirculation.10 guinea pigs' posterior ampullae cristae blood flow were measured with Laser Doppler Flowmetry. Results:cochlear flow was 318.39±91.66mV.Cristae of posterior ampullae was 194.00±45.26mV.The arterial blood pressure was stable in 9. 99～10. 27kPa.The present results showed cochlear and vestibular blood flow were 62.14% and 37.86% in total inner ear blood circula-tion.The latter appeared to be about one half of cochlear blood flow.These suggested that the blood flow of posterior ampullae can reflect the blood flow of vestibular to some degree.Laser Doppler was technically simple,non-invasive,highly stable,reproducible and sensitive.

关 键 词：激光 半规管 耳蜗 血流速度 

分 类 号：R339.16[医药卫生—人体生理学] R446.119[医药卫生—基础医学]