芳香二脒类化合物合成及抑菌活性的初步研究  

Synthesis and fungicidal activity of aromatic diamidines

作　　者：廉应江[1] 陈安良[1] 冯俊涛[1] 张兴[1] 

机构地区：[1]西北农林科技大学无公害农药研究服务中心,陕西杨凌712100

出　　处：《西北农林科技大学学报（自然科学版）》2005年第7期45-48,共4页Journal of Northwest A&F University(Natural Science Edition)

基　　金：国家"十五"科技攻关重大专项(2002BA516A04);西北农林科技大学科研专项

摘　　要：以4-氰基苯酚与α,ω-二溴烷烃为原料,合成了15个芳香二脒类化合物A2～A6,B2～B6和C2～C6,其结构均经1H-NMR和MS确定。初步杀菌试验结果表明,各化合物在质量浓度为10mg/L时,对番茄灰霉病菌(Botrytiscinerea)、白菜黑斑病菌(Alternariabrassicae)和苹果干腐病菌(Botryosphaeriadothidea)等具有较高生物活性,特别是对番茄灰霉病菌,在10mg/L质量浓度下有8个化合物对其抑制率超过90%。A series of aromatic diamidino compounds were synthesized from 4-cyanophenol and α,ω-dibromopane.All compounds were confirmed by 1H NMR and MS.Preliminary biossays showed that some compounds had fungicidal activities in Botrytis cinerea,Alternaria brassicae and Botryosphaer iadothidea at the concentration of 10 mg/L.The inhibition rate of eight compounds on B.cinerea reached 90% at the concentration of 10 mg/L.

关 键 词：戊烷脒 芳香二脒 杀菌活性 

分 类 号：TQ450.11[化学工程—农药化工]