1 065例健康汉族人Brugada心电图征发生率的初步调查  

Preliminary studies of prevalence of electrocardiographic sign of Brugada syndrome in 1 065 healthy Han Chinese

作　　者：杨兵[1] 曹克将[1] 单其俊[1] 李库林[1] 夏耘[1] 涂静[1] 袁斌斌[1] 龚杰[1] 

机构地区：[1]南京医科大学第一附属医院心血管内科,210029

出　　处：《中华心律失常学杂志》2005年第3期214-217,共4页Chinese Journal of Cardiac Arrhythmias

基　　金：江苏省教委基金(04KJB320087);南京医科大学基金(hfg008;CX2003015;NY20003)

摘　　要：目的通过调查健康体检者Brugada心电图征的发生率,获得中国人Brugada综合征的流行病学资料。方法对连续1069例参加年度健康体检的公务员进行病史、家庭史询问、体检、X线胸片和标准12导联心电图检查,按照欧洲心脏病学会推荐标准筛选出Brugada心电图征。结果排除4例器质性心脏病患者后,共1065例(男性805例,女性260例)入选,年龄18～83平均(38.58±15.26)岁。其中39例有黑史,36例有晕厥史,7例有猝死家族史。共8份心电图符合阳性标准,占总例数7.5‰。所有携带者均为男性,心电图均呈鞍型,其中符合Ⅱ型和Ⅲ型者各4例,1例(N7)有黑和晕厥史。结论Brugada心电图征在中国健康汉族人中并不少见,男性多见,其临床意义有待于进一步随访研究证实。Objective To evaluate the prevalence of electrocardiographic sign of Brugada syndrome in healthy Han Chinese .Methods The study subjects consisted of 1 069 consecutive government official while making annual health examination during May 11 to 29, 2004. All subjects underwent history, physical examination, chest x-ray, and standard 12 leads ECG. The diagnostic criteria recommend by European Society of Cardiology was used to identify subjects with electrocardiographic sign of Brugada syndrome. Results One thousand and sixty-five healthy subjects [age 18~83 years, mean(38.58±15.26)years, 805 males and 260 females] were enrolled in this study excluded four patients with cardiovascular disorders. There were 39 subjects had episodes of pre-syncope, 36 had syncope, and seven had family history of sudden death. Electrocardiographic signs of Brugada syndrome were found in 8 male subjects(7.5‰). All these carriers had saddleback type, in whom there were 4 cases with the type Ⅱ ECG and another 4 subjects with type Ⅲ ECG. There was no subject with type ⅠECG. One carrier(N_7) had episodes of pre-syncope and syncope. Conclusion Electrocardiographic sign of Brugada syndrome was not uncommon in healthy Han Chinese, and further studies on its clinical significance is required.

关 键 词：Brugada心电图 发生率 健康汉族人 初步调查 BRUGADA综合征 欧洲心脏病学会 流行病学资料 健康体检者 心电图检查 心脏病患者 12导联 X线胸片 阳性标准 随访研究 临床意义 晕厥史 公务员 家庭史 器质性 男性 家族史 携带者 

分 类 号：R541.7[医药卫生—心血管疾病]