孕妇及新生儿沙眼衣原体感染的临床观察  

The clinical observation of pregnancy with chlamydia trachomatis infection

作　　者：丁瑛[1] 顾惠珍 龚培娥 董金瀚 

机构地区：[1]上海市长宁区妇幼保健院,上海市第一妇婴保健院

出　　处：《中华妇产科杂志》1995年第2期74-76,共3页Chinese Journal of Obstetrics and Gynecology

摘　　要：应用荧光抗体染色法和微量免疫荧光法，对１９９２至１９９３年间１３８９例妊娠１２至２０周的孕妇，于初诊时采集官颈管内分泌物及孕妇时静脉血，检测沙眼衣原体（衣原体）抗原和抗体，并对已分娩的７７２例进行了母婴妊娠结局的比较。结果：衣原体的感染率为１２．７％，衣原体抗原阳性组的胎膜早破、早产、新生儿窒息及胎儿宫内感染率均明显高于阴性组（Ｐ＜０．０１），合并乙型肝炎和霉菌性阴道炎者也明显高于阴性组。提示：衣原体的检测应列为产前常规检查的项目。From 1992 to 1993, 1389 cases of pregnancy at 12～20 gestational weeks were investigated. At first antenatal visit the samples of cervical secretion were taken for chlamydiaI trachomatis antigen test and blcod samples were tested for antiberly simultaneously. Micro immunofluorescence method(MIF)was used for both tests. The chlamydia trachomatis infection rate was 12.7%in Shanghai area. Among 1389 cases,772 were delivered. The maternal and perinatal outcomes were analyzed 772 cases were di-vided into three groups: 82 cases of antigen positive group,55 cases of antibOdy positive group and 635 cases of antigen and antibody negative group.The results showed that the obstetrical complications such as premature rupture of membrance(PROM),premature labor,low Apgar score neonatal asphyxia. neonatal infections and perinatal mortality rate were significantly higher in positive groups than that of negative group(P<0. 001～0.02).The incidence of infections with hepatitis B and candida vaginitis also much higher in positive group. The pathological mechanism of chlamydia trachomatis infection and predisposing high risk factors were discussed in this paper. It suggests that test of chlamydia trachomatis should be included in routine items of antenatal clinic.

关 键 词：沙眼衣原体 胎膜破裂 孕妇 新生儿 

分 类 号：R714.251[医药卫生—妇产科学]