骨巨细胞瘤细胞DNA含量与病理分级和复发的关系  

Flow Cytometric DNA Analysis and its Relation-ship witk Pathology and Prognos is of G ia nt CelI Tu-mor of Bone

作　　者：扈文海[1] 石奉文[1] 张惠民[1] 张标[1] 陈百成[1] 左连富[1] 陈燕[1] 吴世祥[1] 

机构地区：[1]河北医学院第三医院,河北省肿瘤研究所

出　　处：《中华骨科杂志》1995年第12期834-836,共3页Chinese Journal of Orthopaedics

摘　　要：用流式细胞仪对３４例骨巨细胞瘤细胞ＤＮＡ含量和细胞增殖周期（Ｓ％）进行分析，探讨骨巨细胞瘤与病理分级和复发的关系。结果表明：随着分级的增高，ＤＩ值、Ｓ％期细胞亦增高，但Ⅱ级和Ⅲ级Ｓ％期细胞比率差异无显著意义，各级之间倍体水平差异无显著意义，虽然异倍体复发率高，但复发主要受治疗方法的影响。AbstractDNA content and proportion of phase S cells in 34giant cell tumor of bone (GCT)were analysed by flowcytometry. The resuIts showed that DNA index and8%phase cells increased with pathologic grades,butthere was not significant difference in DNA index of8%phase cells of grade Ⅱ and Ⅲ. DNA ploidy wasnot significant among GCT of various grades. The re-currence rate of GCT with DNA aneuploigy was high,however the relapse was influenced mainly by themethod of the treatment.

关 键 词：巨细胞瘤 DNA 骨肿瘤 病理学 复发 

分 类 号：R758.102[医药卫生—皮肤病学与性病学]