再注射^（201）T1心肌SPECT显像检测缺血存活心肌的临床应用  

￣(201)T1 MYOCARDIAL SPECT WITH REINJECTION FOR THE DETECTION OF ISCHEMIC BUT VIABLE MYOCARDIUM

作　　者：何作祥 刘秀杰 寇文镕 史蓉芳 刘蕴忠 余坚芳 

机构地区：[1]中国医学科学院阜外医院核医学科

出　　处：《中华核医学杂志》1995年第3期139-141,共3页Chinese Journal of Nuclear Medicine

基　　金：国际原子能机构(IAEA)资助

摘　　要：对２０例冠心病患者（１９例心肌梗塞）行２０１Ｔ１再注射心肌ＳＰＥＣＴ显像，评价其检测缺血存活心肌的价值．方法：所有患者运动高峰时静脉注射２０１后分别行即刻、４小时＂再分布＂及再注射ＳＰＥＣＴ显像．结果：２０例患者运动后即刻显像显示心肌灌注异常，４小时“再分布”显像有可逆性灌注缺损１５例，不可逆性灌注缺损５例；再注射显像显示可逆性灌注缺损１８例，不可逆性灌注缺损２例．节段分析显示，“即刻”显像９３个心肌节段灌注异常，其中４小时“再分布”显像显示可逆性灌注缺损２７个节段（部分“再分布”１３个节段，完全“再分布”１４个节段）；再注射显像均为可逆性灌注缺损；“再分布”显像为不可逆性灌注缺损６６个节段，其中２５个节段（３８％）再注射显像表现为再充填，４１个节段仍为不可逆性灌注缺损．结论：再注射２０１Ｔ１心肌ＳＰＥＣＴ显像检测缺血存活心肌的灵敏度优于２０１Ｔ１“再分布”显像．PURPOSE To evaluate the accuracy of 201T1 myocardial imaging for the detection of ischemic but viable myocardium.METHODS Exercise and 3～4 hr redistribution 201T1 imaging were performed on 20 patients with coronary artery disease (19 with previous myocardial infarction). RESULTS 3～ 4 hr redistribution imaging identitied 27 segments with reversible perfusion defects; all of which were also identified as reversible by reinjection imaging and among 66 segments with irreversible perfusion defects identified by 3～4 hr redistribution imaging, 25 (38%) segments were identified as reversible, 41 (62%) as irreversible by reinjection imaging. CONCLUSION (201)T1 imaging with reinjection has a better sensitivity for detecting ischemic but viable myocardium in comparison with 3～ 4 hr redistribution imaging.

关 键 词：冠心病 心肌 心放射图描绘 放射性核素 脏器照射 

分 类 号：R541.404[医药卫生—心血管疾病] R817.42[医药卫生—内科学]