2-(1-溴-2-萘氧甲基)-5-芳基-1,3,4-噁二唑的合成与表征  

Synthesis and Characterization of 2-(1-Bromo-2-naphthoxymethyl)-5-aryl-1,3,4-oxadiazoles

作　　者：李德江[1] 张吉斌[1] 傅和青[2] 

机构地区：[1]郧阳师范专科学校化学系,湖北丹江口442700 [2]华南理工大学化工学院化工研究所,广东广州510640

出　　处：《合成化学》2005年第4期361-363,377,共4页Chinese Journal of Synthetic Chemistry

基　　金：湖北省教育厅科学技术研究资助项目(2004D001)

摘　　要：以碳酸钠作缚酸剂,1-溴-2-萘氧甲酰肼与芳酰氯反应制得N,N′-二酰基肼,后者在POCl3作用下脱水环化成2-(1-溴-2-萘氧甲基)-5-芳基-1,3,4-噁二唑。其结构经1HNMR,IR,MS和表征元素分析,并对其裂解途径进行了探讨。2-(1-Bromo-2-naphthoxymethyl)-5-aryl-1,3,4-oxadiazoles were synthesized by cyclization of N,N′-diacylhydrazines with POCl_3. N,N′-diacylhydrazines was obtained from 1-bromo-2-naphthoxyacetyl hydrazine and aroyl chloride using Na_2CO_3 as acid acceptor. The structures were characterized by ~1H NMR, IR, MS and elemental analysis, and the fragmentation mechanism of MS spetra was discussed as well.

关 键 词：噁二唑 二酰基肼 合成 表征 

分 类 号：O626.24[理学—有机化学] TQ251.1[理学—化学]