温肾益心丹为主治疗充血性心力衰竭临床观察  

Clinical Observation on the Effects of Wenshenyixin Pill in Treating Congestive Heart Failure

作　　者：姚淮芳[1] 胡业彬[1] 程晓昱[1] 汪健[1] 张皖东[2] 张叶祥[1] 

机构地区：[1]安徽中医学院第一附属医院干部病房心血管内科,安徽合肥230031 [2]中国中医研究院基础研究所

出　　处：《安徽中医学院学报》2005年第4期4-7,共4页Journal of Anhui Traditional Chinese Medical College

基　　金：安徽省教育厅自然科学基金项目(2003kj246)

摘　　要：目的:观察温肾益心丹为主治疗充血性心力衰竭的临床疗效.方法:31例患者根据住院前后顺序随机分为对照组与研究组,统一根据美国纽约心脏学会(NYHA)心功能分级及中医症状量化记分,并制订统一疗效判定标准;对照组予常规西医药治疗,研究组在常规治疗剂量1/2～2/3基础上加温肾益心丹,疗程为2周;治疗前及疗程中每天对心功能分级及中医量化记分.结果:研究组和对照组治疗前后自身比较,NYHA心功能分级均有改善,差异显著,中医症候积分疗效也有显著改善.研究组与对照组组间比较,NYHA心功能分级疗效判定研究组优于对照组,但差异无显著性(P>0.05);中医症候积分疗效判定研究组优于对照组,差异有显著性(P<0.05);研究组心功能和中医症候改善起效时间均明显早于对照组(P<0.05).结论:温肾益心丹结合西医基础治疗能有效改善充血性心力衰竭患者心功能,尤其能改善心力衰竭患者的中医症候,且其治疗起效时间早.Objective:To investigate the effects of Wenshenyixin Pill combined with conventional western medicine therapy in treating congestive heart failure(CHF). Method: Thirty-one patients with CHF were randomly divided into two groups. The control group (15 cases ) was treated by conventional western medicine therapy,the trial group (16 cases ) added with Wenshenyixin Pill .The course was two weeks . The changes of the cardiac function and the clinical symptoms and physical signs were detected at baseline and every day during treatment. Result: After treatment, the cardiac function in two groups were significantly improved (P<0.05). The clinical symptoms and physical signs in the trial group were more significantly improved than those in control group (P<0.05). Conclusion: Wenshenyixin Pill combined with conventional western medicine therapy can improve the cardiac function of patients with CHF markedly and rapidly.

关 键 词：充血性心力衰竭 温肾益心丹 

分 类 号：R541.61[医药卫生—心血管疾病]