深静脉瓣膜修复成形术治疗下肢慢性静脉功能不全的随机对照临床研究  

Effect of external vavuloplasty of deep vein in the treatment of chronic venous insufficiency of lower extremity

作　　者：王深明[1] 胡作军[1] 李松奇[1] 黄雪玲[1] 叶财盛[1] 

机构地区：[1]中山大学附属第一医院血管外科,广州510080

出　　处：《中华外科杂志》2005年第13期853-856,共4页Chinese Journal of Surgery

摘　　要：目的探讨深静脉瓣膜修复成形术在下肢慢性静脉功能不全治疗中的作用与疗效。方法30例双下肢慢性静脉功能不全的患者接受静脉系统手术治疗。每例2条肢体各采取不同手术方式并随机分组。1条患肢行股浅静脉外瓣膜复成形术加浅静脉手术(A组);另1条患肢仅行浅静脉手术(B组)。术后1个月和3年,利用彩超、流速剖面图彩超技术、空气体积描记仪(APG)和静脉功能不全评分等方法,比较各例2条肢体的疗效以及2组间疗效。结果全组30例患者60条肢体均为CEAP临床分级(Kistner分级)C2～C4级,经彩超和下肢静脉造影证实深静脉瓣膜功能不全返流均为Ⅲ度。术后1个月和3年随访比较,各例属于A组的患肢在静脉返流度、静脉返流量及各项指标均比属于B组患肢改善明显;A组的静脉返流量、静脉灌注指数均值与B组比较差异有统计学意义(P<0.001)。2组的静脉返流度比较差异有统计学意义(P<0.05)。3年随访时2组的射血分数和剩余容量分数均值比较差异有统计学意义(P<0.05);静脉功能不全评分均值比较差异有统计学意义(P<0.001)。结论深静脉瓣膜修复成形术可使下肢深静脉返流量明显减少,瓣膜功能明显恢复,与下肢浅静脉手术联合治疗下肢慢性静脉功能不全有更好的疗效。Objective To verify the role and effect of external vavuloplasty in the treatment of chronic venous insufficiency(CVI) of lower extremity. Methods Thirty patients with CVI of bilateral lower extremities were enrolled to accept surgical management of vein systems. Both limbs of each patient were randomized into two groups respectively according to the operating style. One limb was given external vavuloplasty of the superficial femoral vein and surgery of superficial venous system( group A), the another limb was only given the surgery of superficial venous system (group B). The effect comparison between both limbs of each patient and two groups by color duplex scanning、color doppler velocity profile (CDVP)、air plethysmography and CEAP score system one month and 3 years after operation. Results All 60 limbs of 30 cases were CEAP C_2~C_4 with degree Ⅲ reflux (Kistner′s method) in the deep veins confirmed by color duplex scanning and venography. In 1 month and 3 years after surgery, all the indexes of the limb in the group A were dramatically improved compared with those of the limbs in the group B. The average value of venous reflux degree, reflux volume, and venous filling index(VFI) had significant difference between the two groups (P<0.001). In 3 years after surgery, there was significant difference between the two groups on ejective fraction (EF)and residual volume fraction(RVF) (P<0.05) and CEAP clinical score (P<0.001). Conclusion External vavuloplasty of deep vein may reduce the reflux volume of the affected deep vein and improve the valve function, and can result in better outcomes when combined with surgery of the superficial venous system.

关 键 词：下肢慢性静脉功能不全 瓣膜修复成形术 随机对照临床研究 深静脉瓣膜功能不全 浅静脉手术 空气体积描记仪 下肢静脉造影 静脉返流 下肢深静脉 统计学 手术治疗 静脉系统 随机分组 手术方式 股浅静脉 流速剖面 临床分级 

分 类 号：R654.3[医药卫生—外科学]