老年NIDDM患者尿液微量转铁蛋白检测的临床意义  

Clinical significance of microtransferrinuria in the aged with NIDDM

作　　者：梁琳琅[1] 盛志业[1] 刘国良[1] 刘苏燕[1] 傅炜昕[1] 

机构地区：[1]解放军沈阳军区总医院,中国医科大学第一临床学院

出　　处：《中华老年医学杂志》1995年第6期348-351,共4页Chinese Journal of Geriatrics

摘　　要：对９６例非胰岛素依赖型糖尿病（ＮＩＤＤＭ）患者尿液微量转铁蛋白排泄率（ＴＥＲ）作了临床研究。结果显示，老年患者ＴＥＲ（６２例，７．１７±０．９６μｇ／ｇ·Ｃｒ）高于健康老年对照组（１９例，０．４２±０．１７μｇ／ｇ·Ｃｒ）及非老年患者（３４例，３．３０±０．８９μｇ／ｇ·Ｃｒ）（Ｐ均＜０．０１）。其增高程度与蛋白尿、肾功能状态、糖尿病病程及视网膜病变程度关系密切。尿微量转铁蛋白检测是预测老年糖尿病患者是否并发早期糖尿病肾病的指标之一。Abstract The excretion rations of urinary microtransferrin or transferrin excretion rate(TER)in 96 non-insulin-dependent diabetic patients were deftermined.Urinary TER values in aged diabetics (n= 62,7.17± 0.96μg/g.Cr) were significantly higher than those in normal control(n= 19 , 0.42 ± 0.17 μg/g.Cr) and non-aged diabetics(n= 34,3.30 ± 0. 89μg/g.Cr)(P< 0.01).The increase of TER was closely related with presence of function of kidney,duration of diabetes mellitus and retinopathy parameter to predict inlitial diabetic nephropathy.

关 键 词：糖尿病 糖尿病性肾病 尿 转铁球蛋白 

分 类 号：R587.102[医药卫生—内分泌]