高压氧对小鼠脾细胞IL－2产生及反应能力的影响  

Effect of Hyperbaric Oxygen(HBO) on Splenic Lymphocyte IL-2 Reproduction and Reactivity in Mice

作　　者：张海鹏[1] 邓欣[1] 田伟[1] 王燕[1] 郝鸣政[1] 王秀荣[1] 

机构地区：[1]中国医科大学病理生理教研室,中国医科大学第一临床学院高压氧科

出　　处：《中华理疗杂志》1995年第4期198-199,共2页Chinese Journal of Physical Therapy

基　　金：国家自然科学基金

摘　　要：Ｃ５７ＢＬ／６小鼠在０．２５ＭＰａ下吸９９．２％氧，其脾淋巴细胞白细胞介素－２（ＩＬ－２）产生能力及对ＩＬ－２反应能力变化如下：高压氧（ＨＢＯ）组均明显低于正常组小鼠，去肾上腺组、去肾上腺髓质组均明显高于ＨＢＯ组、假手术组．实验证明，高压氧可降低脾淋巴细胞ＩＬ－２的产生及对ＩＬ－２的反应能力，在这一影响中肾上腺有一定作用．In the paper,the splenic lymphocyte IL-2 reproduction and reactivity of 60 male mice with C57BL/6 were observed,when they were put into the HBO chamber with 0.25MPa and inspired 99.2% oxygen.The result:The indexes as mentioned above were remarkably decreased in HBO group compared with those of normal mice.But the indexes in adrenallectomy and medullectomy group were higher than those of HBO and pseudo-operation group.It is proved that the HBO may reduce the splenic lymphocyte IL-2 reproduction and reactivity,in which the adrenal gland may play an important role.

关 键 词：高压氧治疗 淋巴细胞功能 白细胞介素-2 

分 类 号：R459.6[医药卫生—治疗学]