消毒剂破坏乙、丙型病毒性肝炎血清标志物的初步观察  

Prelimimary Observation on the Destructive Effect of Chemical Disinfectants in serum Markers of Hepatitis B and C

作　　者：杨世明[1] 杨枨林[1] 安仁鸣[1] 解华[1] 

机构地区：[1]解放军第四军医大学唐都医院血库

出　　处：《中华流行病学杂志》1995年第3期154-156,共3页Chinese Journal of Epidemiology

摘　　要：笔者采用氯仿、４０％甲醛溶液、３％双氧水及７５％乙醇与ＨＢｓＡｇ、ＨＢｅＡｇ和抗－ＨＣＶ阳性血清作用５、１５、３０及６０分钟后，用ＥＬＩＳＡ法检测是否转为阴性，以了解消毒剂对上述阳性血清的破坏效果。结果：氯仿对ＨＢｓＡｇ和抗－ＨＣＶ阳性血清破坏效果好；４０％甲醛溶液对ＨＢｓＡｇ、ＨＢｅＡｇ及抗－ＨＣＶ阳性血清均破坏；３％双氧水对ＨＢｅＡｇ有破坏作用，而７５％乙醇对ＨＢｓＡｇ、ＨＢｅＡｇ及抗－ＨＣＶ阳性血清作用上述时间后，检测时仍呈阳性反应。笔者只是初步观察，有关消毒剂的浓度、效果及作用机理有待进一步观察和探讨。hloroform,40%formaldehyde,3%hydrogen peroxide solution and 75%alcohol were usedto act on hepatitis B surface antigen(HBeAg),hepatitis B e antigen(HBaAg)and anti-hepatitisC virus antibody(Anti-HCV)positive serum for 5,15,30 and over 60 minutes.They were exam-ined by enzyme-linked immunosorbent assay and observed for the effect.The destructive effect of chloroform on HBsAg and anti-HCV positive derum was marked.Itwas discovered that 40%formaldehyde solution destroyed HBsAg,HBeAg,and anti-HCV positiveserm,while 75%alcohol also showed destructive effect on HBsAg,HBeAg and anti-HCV positive serum.

关 键 词：乙型肝炎病毒 丙型肝炎病毒 消毒剂 消毒 

分 类 号：R187.1[医药卫生—流行病学] R373.2[医药卫生—公共卫生与预防医学]