我国部分脊髓灰质炎高发省急性弛缓性麻痹病例发病情况调查  

An Investlgation on Acute Flaccid Paralysis(AFP)Cases i n some Provinces with high Risk of Po-Iiomyelitis of China

作　　者：王钊[1] 杨保平 李慧芳 张荣珍[1] 张振馨 周军[1] 董胜利[1] 张健 李全乐 张兴录 戴斐 徐爱强 陈小春 楚金贵 

机构地区：[1]卫生部疾病控制司,中国预防医学科学院,协和医院,山东省卫生防疫站,湖南省卫生防疫站,河北省卫生防疫站

出　　处：《中华流行病学杂志》1995年第3期131-136,共6页Chinese Journal of Epidemiology

摘　　要：１９９４年６月中旬卫生部疾病控制司专业考察小组，在我国一个脊髓灰质炎（脊灰）高发省份随机抽取２０个地区，对其４５所地（市）级和１３所县级医院进行了ＡＦＰ病例的主动搜索，共查出１９９１～１９９４年５月发病的ＡＦＰ病例６８１例，分布于１０１个县市。结果表明：０～１４岁儿童ＡＦＰ、脊灰、非脊灰ＡＦＰ及ＧＢＳ年平均发病率分别为１．０４／１０万、０．４８／１０万、０．５７／１０万及０．３１／１０万，其中脊灰发病率明显较１９９１年下降，其构成比由１９９１年的第一位逐年降低；此外，约９５％的脊灰患者分布于０～４岁组，表明０～４岁儿童应为今后监测和保护的重点；非脊灰ＡＦＰ发病率具有明显的地区性差异，认为采用“０～４岁非脊灰ＡＦＰ发病率＞１／１０万”作为监测系统敏感性指标似更合乎国情。n the mid Jun,1994,a study team organized by MOPH investigated AFP cases in 10 provinceswith high prevalence of poliomyelitis(polio). Twenty prefectures and ten counties were selectedrandomly from each of 10 provinces and relevant prefectures. The team identified 681 AFP casesunder 15 years old from 45 hospitals at prefecture level and 13 hospitals at county level based onhospital records from cases occurred during 1991-1994.AFP,Polio,Non-polio AFP and GBS(Guillian-Barre Syndrome)cases aged from 0=14 years scattered around 101 counties(cities)a-mong target population and their average incidences by year were 1.04,0.48,0.57 and 0.31(per10￣ 5)respectively.Noticingly,the incidence of polio had reduced significantly since 1991,and itsproportion among AFP was also reducing from first place yearly since 1991.In addition, over 95%of the polio cases were concentrated in the 4 year olds which indicated that the target populationfor surveillance and prevention should mainly be focusing on 0-4 year olds. As the incidence of non-polio AFP has been used as a current sensitive index of surveillance system,we noticed that theincidence rates had been significantly different from various regions. According to the analytic da-ta, we recommend that ″Rate of non-polio AFP in children 0-14 years of age greater than 1/10￣5″,might be a better and more sensitive index for surveillance program in China.

关 键 词：弛缓性 麻痹 发病率 脊髓灰质炎 后遗症 

分 类 号：R682.21[医药卫生—骨科学]