多种细菌酶治疗尿毒症的临床观察  

USE OF MICROENCAPSULATED PRODUCTS OF BACTERIAL ENZYMES IN TREATMENT OFUREMIA

作　　者：张庆怡[1] 陈素英[1] 黄佩文 钱家麒[1] 

机构地区：[1]上海第二医科大学附属仁济医院肾内科

出　　处：《中华肾脏病杂志》1995年第3期130-132,共3页Chinese Journal of Nephrology

摘　　要：应用细菌酶微囊制剂治疗尿毒症病人３０例，随机分为三组，第三组应用０．５ｇ·ｋｇ￣－１／ｄ剂量治疗二周者疗效最佳，经统计学分析第三组治疗后ＢＵＮ和肌酐均下降显著（Ｐ＜０．０５和Ｐ＜０．０１），治疗前后回归直线比较７／９例有效，Ｃｃｒ７／１０例好转与回归直线检测相一致，示预后亦有改善。he paper reported 30 cases of patients with ure-mia were treated by microencapsulated products of bac-terial enzymes. They were diveded into 3 groups at ran-dom, among these 3 groups, groupe Ⅲ in orally dose0. sg. kg-1.d treatmg for 2 weeks was more effectivethan other two groups. BUN and Scr were decreasedevidently in comp rison before and after treatment sig-nificantly different (respectively P < 0.05 and P <0.01).The results of the therapy demonstrated thatbefore and after the therapy, 7 of 9 cases were good inthe difference of the two recurrent lines. The level ofCcr in 7 of 10 cases was increased , which was the sameas the recurrent line. Our study dernonstrated that mi-croencapsulated products of bacterial enzymes couldslow down the progression.

关 键 词：尿毒症 药物疗法 细菌酶 脲酶 肌酐酶 

分 类 号：R695.05[医药卫生—泌尿科学]