脂肪乳剂糜蛋白酶预防腹腔内粘连的研究  

Experimental study on the prevention ofperitoneal adhesion using intralipid and chymotrypsin

作　　者：汤义军[1] 孙广荣[1] 田文[1] 张素兰[1] 明俊英[1] 王新[1] 

机构地区：[1]山东烟台毓璜顶医院

出　　处：《中华实验外科杂志》1995年第3期155-156,共2页Chinese Journal of Experimental Surgery

摘　　要：选用新西兰白兔４８只，分成三组，制成肠粘连模型，分别用１０％脂肪乳剂、糜蛋白酶超声混合液，６％右旋糖酐（Ｄ＿（４０））腹腔灌注，分别与对照组比较，结果显示，两组均有显著预防腹腔内粘连作用（Ｐ＜０．０１，Ｐ＜０．０５）。而１０％脂肪乳剂、糜蛋白酶的作用较右旋糖酐更显著（Ｐ＜０．０１）。Forty-eight New Zealand white rabbitsselected which were made as the models ofperitoneal adhesion were given peritoneallavage using a mixture of 10%intralipid andchymotrypsin,and 6%dextran(D_(40))respec-tively.Compared with the control group,theresults showed significant effect of peritonealadhesion prevention in both growh(P<0.01)、(P<0.05).The effect of 10%in-tralipid and chymotrypsin is more obviousthan that of dextran(P<0.01),and it may beused as a good method to prevent the peri-toneal adhesion.

关 键 词：脂肪乳剂 糜蛋白酶 腹腔内粘连 

分 类 号：R656.06[医药卫生—外科学] R619.901[医药卫生—临床医学]