同种原位心脏移植一例报告  

Orthotopic heart transplantation :a case report

作　　者：景华[1] 丁永清[1] 李忠东[1] 高声甫[1] 周采璋[1] 张石江[1] 李德闽[1] 张希龙[1] 周志友[1] 顾卫东[1] 许飚[1] 徐建国[1] 吴北京 朱清於[1] 储小曼[1] 

机构地区：[1]南京军区总医院心胸外科,南京军区总医院麻醉科,南京军区总医院病理科,南京军区总医院药理科

出　　处：《中华外科杂志》1995年第9期559-560,共2页Chinese Journal of Surgery

摘　　要：１９９４年７月，作者为１例曾施行过心内直视手术右心室流出道拓宽的肥厚性心肌病患者，成功地进行了同种异体原位心脏移植术。术后恢复顺利。按照三联免疫治疗的方法行抗排异治疗。患者曾三次出现急性排异反应，应用甲基强的松龙冲击治疗均获有效控制。现已术后１年，患者心、肝、肾功能正常，已参加正常工作。作者还对供心采取、心肌保护、手术方法、术后免疫监测、抗排异和抗感染治疗等进行了介绍。AbstractIn July 1994,we performed orthotopic hearttransplantation for a patient with hypertrophic my-ocardiopathy, who had had open heart surgery enlarg-ing the right ventricular outlet. The patient had an ex-cellent postoperative result.He received triple-drugimmunosuppressive therapy.Large dose of methyl-prednisolone was used successfully for his acute rejec-tion reaction. At present,the patient is living wellwith good cardiac hepatic and renal function. We de-scribed donor heart harvest,myocardial protection ,op-erative procedure,immune monitoring,anti-rejectionand anti-infectious therapy. We introduced the processof protecting donor heart on the way to hospital by ret-rograde perfusion with medium hypothermic oxygenat-ed-blood combined with St,Thomas cardioplegia. Be-sides endomyocardial biopsy , other noninvasive exami-nations such as noninvasive cardiac output monitoringcould be helpful to monitor acute rejection reaction.

关 键 词：同种移植 移植 

分 类 号：R654.205[医药卫生—外科学]