CO_2超声造影对鼠肝影响的观察  

Observation of Effect ot Carbon Dioxide Contrast Ultrasonography on the Rat Liver

作　　者：王文平[1] 徐智章[1] 刘利民[1] 邵渊[1] 黄备建[1] 丁红[1] 

机构地区：[1]上海医科大学附属中山医院超声诊断科

出　　处：《中华物理医学杂志》1995年第3期129-131,共3页Chinese Journal of Physical Medicine and Rehabilitation

基　　金：卫生部青年科学基金

摘　　要：通过对１２只Ｓｐｒａｇｕｅ－Ｄａｗｌｅｙ（ＳＤ）大鼠进行经股动脉肝脏ＣＯ_２超声造影，并与对照组比较，结果显示ＣＯ_２微泡进入肝脏后，血清谷丙转氨酶升高与对照组相比无明显差异；病理切片显示ＣＯ_２组中仅２个有肝细胞灶性脂肪变性；电镜仅显示ＣＯ_２组肝细胞有脂滴存在，但无明确的细胞器改变。实验提示ＣＯ_２微泡对鼠肝未有明确的损害迹象，有临床应用的价值。Twelve rats via CO2 enhanced ultrasonography were analysed by liver function, pathology and electron microscope.The SGPT level in serum of CO2 group was higher than that for control group, but was not significant difference between two groups. The pathlogical change of the rat liver was not found in CO2 group and control grop.The electron microscope showed that there lipid within the liver cells,but the injurious change of the organella within the liver cells was not found. Therefore, CO2 contrast was relatively safe for the liver.

关 键 词：鼠肝 二氧化碳 超声波诊断 

分 类 号：R445.1[医药卫生—影像医学与核医学]