子宫内膜异位症发病与个体因素的关系  

Personal characteristics as risk factors of endometriosis

作　　者：潘凌亚[1] 宋鸿钊[1] 吴葆桢[1] 韩美龄 

机构地区：[1]北京协和医院妇产科

出　　处：《中华医学杂志》1995年第1期34-36,共3页National Medical Journal of China

基　　金：国家自然科学基金

摘　　要：通过对２０３例盆腔子宫内膜异位症和４０６例随机人群对照的流行病学调查，发现子宫内膜异位症的发生可能与是否受过高等教育、体重、个人疾病史、Ａ血型及妇科疾病家族史等因素有关。提示，月经血倒流是子宫内膜异位症形成的基础，是否发病还取决于机体神经、内分泌和免疫系统的健全，以及由遗传等因素决定的人体易感性。03 patients with pelvic endometriosis, all Beijingresident were collected from the Peking Union MedicalCollege Hospital and the Beijing Obstetrical and Gyneco-logical Hosprtal. The diagnosis of endometriosis wasconfirmed by pathological examination of surgical speci-mens in 186 patients and by aspiration of chocolate sub-stance under laparoscopy in 17. Two population con-trols, age matched± 1 year . were randomly selected foreach patient from the same residential area , after carefulpelvic exarninations and ultrasonographies. A question-aire for any possible risk factors to endornetriosis was de-veloped and with this questionaire a face to face inter-view for each subject was carried out by the trained in-terviewers. All interviews were tape recorded and calcu-lated in a AST 386 computer. The continuous logisticregression for matched stes was used to obtain a maxi-mum likelihood point and to control the potential con-founding effects of selected variables. Relative risk(RR) substituted for odds ratio together with the 95%confidence intervals was estimated. All the resuhs wereadjusted for the variables of the model including somerelevant factors of menstruation, pregnancy and contra-ception. An increased risk for endometriosis was foundto be related to women who had a higher level of educa-tion. Even it was adjusted for age of first marriage andpregnancy , gravidity, parity , contraception and all oth-er variables of the model, the relative risk was 1. 84 forendometriosis. Therefore, it is the education level itselfthat plays a true role in development of endometriosis.Although there was a trend in risk for endometriosis inheight, it was statistically insignificant. Weight howev-er, is a better predictor than height of risk for en-dometriosis. There was a significantly greater risk of en-dometriosis for women who und

关 键 词：子宫内膜异位症 流行病学 

分 类 号：R711.71[医药卫生—妇产科学]