硬质合金粉尘致肺纤维化作用的流行病学调查  

An Epidemiologic Study on Pulmonary Fibrosis Caused by Hard Alloy Dust

作　　者：邹世渠[1] 邹彤彤[1] 马伏生[1] 刘文毅[1] 韩秀荣[1] 祖翠义[1] 张孟桃 尹燕 李毓馨 刘志远 

机构地区：[1]北京医科大学公共卫生学院,北京市劳动卫生职业病防治研究所,四川省自贡市硬质合金厂职工医院,湖南省株洲市硬质合金厂职工医院,陕西省兴平县145医院,黑龙江省牡丹江市职业病防治所

出　　处：《中华预防医学杂志》1995年第2期70-72,共3页Chinese Journal of Preventive Medicine

摘　　要：对我国有代表性的４家硬质合金生产厂及２家工具研磨厂的１２３７名单纯接触硬质合金粉尘工人及５０２名对照工人进行分析，结果表明，接触组呼吸系统症状、肺功能异常检出率、血清铜蓝蛋白及尿钴含量均明显高于对照组。Ｘ线胸片检查发现８例尘肺，患病率为０．６５％，发病平均接尘工龄为２５．２年。上述结果说明，硬质合金粉尘具有致肺纤维化作用，并可引起尘肺。cross-sectional study, with 1 237 employees solely exposed to hald alloy dust and 502 controls in four hard rnetal works and two tool and grinder manufacturers in China,was conducted.Results showed prevalence of symptoms of respiratory system,and abnormalities in lung function and serum lev-el of ceruloplasmin and urine cobalt content in exposed group were significantly higher than those in con-trols.Eight cases of pneumoconiosis were detected by chest X-ray filmLs with a prevalence of 0.65%and an average length of employment in dust environrnent of 25. 2 years. It suggested hard alloy dust could cause pulmonary firbrosis and pneumoconiosis in exposed workers.

关 键 词：硬质合金 肺纤维化 尘肺 粉尘 流行病学 

分 类 号：R135.2[医药卫生—劳动卫生]